1. Gene
  2. RAB26 - RAB26, member RAS oncogene family Gene

RAB26 - RAB26, member RAS oncogene family Gene

Homo sapiens

Also known as V46133

Gene ID: 25837 | Gene type: protein coding

About RAB26

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:2,148,144-2,154,165 (from NCBI)

This gene has 8 transcripts (splice variants), 250 orthologues and 68 paralogues. Broad expression in brain (RPKM 4.5), salivary gland (RPKM 3.5) and 15 other tissues.

Summary

Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM, Nov 2010]

RAB26 Products(2)

mRNA Protein Name
NM_001308053.1 NP_001294982.1 ras-related protein Rab-26 isoform 2
NM_014353.5 NP_055168.2 ras-related protein Rab-26 isoform 1

RAB26 Protein Structure

Ras

Ras: Ras family (65 - 226)

  • 0
  • 100
  • 200
  • 256 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-26

Ras-related oncogene protein

Related Diseases

Diseases Alias
Spastic Paraplegia 15, Autosomal Recessive

SPG15

Kjellin Syndrome

Hereditary Spastic Paraplegia 15

Spastic Paraplegia And Retinal Degeneration

Autosomal Recessive Spastic Paraplegia Type 15

Hereditary Spastic Paraparesis Type 15

Spastic Paraplegia-Retinal Degeneration Syndrome

Autosomal Recessive Spastic Paraplegia 15

Spinal Muscular Atrophy, Distal, Autosomal Recessive, 4

DSMA4

Autosomal Recessive Lower Motor Neuron Disease With Childhood Onset

Distal Spinal Muscular Atrophy Type 4

Autosomal Recessive Distal Spinal Muscular Atrophy Type 4

Distal Spinal Muscular Atrophy, Autosomal Recessive, 4

Atrophy, Muscular, Spinal, Distal, Autosomal Recessive, Type 4

Spinal Muscular Atrophy, Type Iv

SMA4

Spinal Muscular Atrophy, Adult Form

Spinal Muscular Atrophy 4

Spinal Muscular Atrophy-4

Adult Spinal Muscular Atrophy

Spinal Muscular Atrophy, Proximal, Adult, Autosomal Recessive

Proximal Spinal Muscular Atrophy Type 4

Sma Type 4

Sma Type Iv

Sma-Iv

Sma Iv

Spinal Muscular Atrophy Adult Form

Spinal Muscular Atrophy Proximal Adult Autosomal Recessive

Spinal Muscular Atrophy Type Iv

Atrophy, Muscular, Spinal, Type Iv

Myelopathic Muscular Atrophy

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus RAB26 VGNC VGNC:80677
Mus musculus RAB26 MGD MGI:2443284
Bos taurus RAB26 VGNC VGNC:33633
Macaca mulatta RAB26 VGNC VGNC:81526
Rattus norvegicus RAB26 RGD RGD:620890
Canis familiaris RAB26 VGNC VGNC:45266