RAI14 - retinoic acid induced 14 Gene

Homo sapiens

Also known as RAI13; NORPEG

Gene ID: 26064 | Gene type: protein coding

About RAI14

Cytogenetic location: 5p13.2 Genomic coordinates (GRCh38): 5:34,656,328-34,832,612 (from NCBI)

This gene has 28 transcripts (splice variants) and 203 orthologues. Broad expression in endometrium (RPKM 27.5), placenta (RPKM 14.1) and 23 other tissues.

Summary

Predicted to enable actin binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of NIK/NF-kappaB signaling; and spermatogenesis. Located in cytosol; fibrillar center; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RAI14 Products(6)

mRNA	Protein	Name
NM_001145520.1	NP_001138992.1	ankycorbin isoform a
NM_001145521.2	NP_001138993.1	ankycorbin isoform a
NM_001145522.2	NP_001138994.1	ankycorbin isoform b
NM_001145523.2	NP_001138995.1	ankycorbin isoform c
NM_001145525.2	NP_001138997.1	ankycorbin isoform d
NM_015577.3	NP_056392.2	ankycorbin isoform a

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	15161933	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAI14 Protein Structure

Ank_2

0
200
400
600
800
980 a.a.

Protein Preferred Names

Protein Names

ankycorbin

ankyrin repeat and coiled-coil structure-containing protein

RAI14 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	RAI14	Q9P0K7	YWHAZ	Homo sapiens	P63104	Pull Down	15161933

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Cardiomyopathy, Infantile Histiocytoid

Histiocytoid Cardiomyopathy	Foamy Myocardial Transformation Of Infancy
Infantile Histiocytoid Cardiomyopathy	Infantile Xanthomatous Cardiomyopathy
Oncocytic Cardiomyopathy	Cardiomyopathy, Infantile Xanthomatous
Cardiomyopathy, Focal Lipid	Cardiomyopathy, Oncocytic
Focal Lipid Cardiomyopathy	Infantile Cardiomyopathy With Histiocytoid Change
CMIH	Cardiomyopathy Focal Lipid
Cardiomyopathy Infantile Xanthomatous	Cardiomyopathy Oncocytic

Twin-To-Twin Transfusion Syndrome

Twin To Twin Transfusion Syndrome	Twin Twin Transfusion Syndrome
Fetal Blood Loss From Fetal Hemorrhage Into Co-Twin	Fetal Hemorrhage Into Co-Twin
Twin To Twin Transfusion	Twin-To-Twin Blood Transfer
Fetal Transfusion Syndrome	Fetofetal Transfusion Syndrome
Ttts	Feto-Fetal Transfusion Syndrome
Fetofetal Transfusion	Fetus-To-Fetus Placental Transfusion Syndrome

Potocki-Lupski Syndrome

PTLS	Chromosome 17p11.2 Duplication Syndrome
17p11.2 Microduplication Syndrome	Duplication 17p11.2 Syndrome
Trisomy 17p11.2	Potocki-Lupski Syndrome (Dup(17)(P11.2p11.2))
17p11.2 Duplication Syndrome	Dup(17)(P11.2p11.2)
Pls	Chromosome 17, Trisomy 17p11 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11625	RAI14 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	RAI14	VGNC	VGNC:45329
Felis catus	RAI14	VGNC	VGNC:64482
Bos taurus	RAI14	VGNC	VGNC:33696
Rattus norvegicus	RAI14	RGD	RGD:1305942
Mus musculus	RAI14	MGD	MGI:1922896
Macaca mulatta	RAI14	VGNC	VGNC:76478

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