WSB1 - WD repeat and SOCS box containing 1 Gene

Homo sapiens

Also known as SWIP1; WSB-1

Gene ID: 26118 | Gene type: protein coding

About WSB1

Cytogenetic location: 17q11.1 Genomic coordinates (GRCh38): 17:27,294,114-27,315,926 (from NCBI)

This gene has 17 transcripts (splice variants), 214 orthologues and 1 paralogue. Ubiquitous expression in spleen (RPKM 64.5), lung (RPKM 63.6) and 25 other tissues.

Summary

This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

WSB1 Products(3)

mRNA	Protein	Name
NM_001348350.2	NP_001335279.1	WD repeat and SOCS box-containing protein 1 isoform 3
NM_015626.10	NP_056441.6	WD repeat and SOCS box-containing protein 1 isoform 1
NM_134265.4	NP_599027.1	WD repeat and SOCS box-containing protein 1 isoform 2

WSB1 Protein Structure

WD40

SOCS_box

0
100
200
300
421 a.a.

Protein Preferred Names

Protein Names

WD repeat and SOCS box-containing protein 1

SOCS box-containing WD protein SWiP-1

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-141482	WSB1 Degrader 1	Inhibitor	99.93%	Unkown
HY-RS15849	WSB1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	WSB1	MGD	MGI:1926139
Macaca mulatta	WSB1	VGNC	VGNC:79186
Felis catus	WSB1	VGNC	VGNC:67091
Canis familiaris	WSB1	VGNC	VGNC:48435
Bos taurus	WSB1	VGNC	VGNC:36971
Rattus norvegicus	WSB1	RGD	RGD:1307835

Name
Email *

	Sorry, but the email address you supplied was invalid.