2. Gene
  3. NOC2L - NOC2 like nucleolar associated transcriptional repressor Gene

NOC2L - NOC2 like nucleolar associated transcriptional repressor Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NIR; NET7; NET15; PPP1R112

Gene ID: 26155 | Gene type: protein coding

About NOC2L

Cytogenetic location: 1p36.33 Genomic coordinates (GRCh38): 1:944,203-959,256 (from NCBI)

This gene has 6 transcripts (splice variants) and 193 orthologues. Ubiquitous expression in testis (RPKM 23.1), skin (RPKM 20.4) and 25 other tissues.

Summary

Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of Histone Acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]).[supplied by OMIM, Mar 2008]

NOC2L Products(1)

mRNA Protein Name
NM_015658.4 NP_056473.3 nucleolar complex protein 2 homolog

NOC2L Protein Structure

Noc2

Noc2: Noc2p family (326 - 623)

  • 0
  • 200
  • 400
  • 600
  • 749 a.a.
Protein Preferred Names Protein Names

nucleolar complex protein 2 homolog

NOC2-like protein

Related Diseases

Diseases Alias
Epiphyseal Chondrodysplasia, Miura Type

ECDM

Tall Stature-Scoliosis-Macrodactyly Of The Great Toes Syndrome

Miura Type Epiphyseal Chondrodysplasia

Tall Stature-Scoliosis-Macrodactyly Of The Halluces Syndrome

Tall Stature-Long Halluces-Multiple Extra-Epiphyses Syndrome

Chondrodysplasia, Epiphyseal, Miura Type
Interstitial Nephritis, Karyomegalic

Karyomegalic Interstitial Nephritis

KMIN

Kin

Systemic Karyomegaly

Karyomegalic Tubulointerstitial Nephritis

Ktn
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09400 NOC2L Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus NOC2L VGNC VGNC:63845
Bos taurus NOC2L VGNC VGNC:32146
Canis familiaris NOC2L VGNC VGNC:43873
Rattus norvegicus NOC2L RGD RGD:1309387
Mus musculus NOC2L MGD MGI:1931051
Macaca mulatta NOC2L VGNC VGNC:75245