2. Gene
  3. FBXO9 - F-box protein 9 Gene

FBXO9 - F-box protein 9 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as FBX9; VCIA1; NY-REN-57; dJ341E18.2

Gene ID: 26268 | Gene type: protein coding

About FBXO9

Cytogenetic location: 6p12.1 Genomic coordinates (GRCh38): 6:53,057,802-53,100,873 (from NCBI)

This gene has 13 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in adrenal (RPKM 15.5), bone marrow (RPKM 13.7) and 25 other tissues.

Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein Ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq, Jul 2008]

FBXO9 Products(3)

mRNA Protein Name
NM_012347.4 NP_036479.1 F-box only protein 9 isoform 1
NM_033480.3 NP_258441.1 F-box only protein 9 isoform 2
NM_033481.3 NP_258442.2 F-box only protein 9 isoform 3

FBXO9 Protein Structure

F-box-like

F-box-like: F-box-like (188 - 238)

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  • 447 a.a.
Protein Preferred Names Protein Names

F-box only protein 9

F-box protein Fbx9

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04815 FBXO9 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus FBXO9 VGNC VGNC:62199
Rattus norvegicus FBXO9 RGD RGD:1310374
Bos taurus FBXO9 VGNC VGNC:28921
Macaca mulatta FBXO9 VGNC VGNC:72492
Mus musculus FBXO9 MGD MGI:1918788
Canis familiaris FBXO9 VGNC VGNC:40791