Meioc - meiosis specific with coiled-coil domain Gene

Mus musculus

Also known as Gm663; Gm1564

Gene ID: 268491 | Gene type: protein coding

About Meioc

Summary

Involved in several processes, including gamete generation; germline cell cycle switching, mitotic to meiotic cell cycle; and synaptonemal complex assembly. Located in cytoplasm and nucleus. Is expressed in meiotic germ cell of ovary; ovary; spermatocyte; and testis. Orthologous to human MEIOC (meiosis specific with coiled-coil domain). [provided by Alliance of Genome Resources, Apr 2022]

Meioc Products(1)

mRNA	Protein	Name
NM_001127576.2	NP_001121048.1	meiosis-specific coiled-coil domain-containing protein MEIOC

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	26742488	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in chromosome organization involved in meiotic cell cycle	IMP IMP: Inferred from mutant phenotype	28380054	MGI
involved in double-strand break repair	IMP IMP: Inferred from mutant phenotype	26742488	MGI
involved in female meiosis I	IMP IMP: Inferred from mutant phenotype	26742488	MGI
involved in germline cell cycle switching, mitotic to meiotic cell cycle	IMP IMP: Inferred from mutant phenotype	28380054	MGI
involved in mRNA stabilization	IMP IMP: Inferred from mutant phenotype	26742488	MGI
involved in male meiosis I	IMP IMP: Inferred from mutant phenotype	26742488	MGI
involved in metaphase chromosome alignment	IMP IMP: Inferred from mutant phenotype	26742488	MGI
involved in oocyte development	IMP IMP: Inferred from mutant phenotype	26742488	MGI
involved in spermatid development	IMP IMP: Inferred from mutant phenotype	28380054	MGI
involved in spermatogenesis	IMP IMP: Inferred from mutant phenotype	26742488	MGI
involved in synaptonemal complex assembly	IMP IMP: Inferred from mutant phenotype	26742488	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	26742488	MGI
located in nucleus	IDA IDA: Inferred from direct assay	28380054	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

meiosis-specific coiled-coil domain-containing protein MEIOC

meiosis-specific with coiled-coil domain protein

Meioc Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Cross	Meioc	A2AG06	YTHDC2	Homo sapiens	Q9H6S0	Anti Tag CoIP	26742488
Intra	Meioc	A2AG06	Ythdc2	Mus musculus	B2RR83	Anti Bait CoIP	26742488
Intra	Meioc	A2AG06	Ythdc2	Mus musculus	B2RR83	Confocal	26742488

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08324	MEIOC Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Meioc	NCBI	NCBI:284071

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