Tnfrsf12a - tumor necrosis factor receptor superfamily, member 12a Gene

Mus musculus

Also known as Fn14; HPIP; TweakR; TWEAK-R

Gene ID: 27279 | Gene type: protein coding

About Tnfrsf12a

Summary

Involved in regulation of angiogenesis. Acts upstream of or within extrinsic apoptotic signaling pathway; positive regulation of axon extension; and substrate-dependent cell migration, cell attachment to substrate. Located in cell surface; plasma membrane; and ruffle. Is expressed in several structures, including adrenal medulla; genitourinary system; heart; limb long bone; and molar. Orthologous to human TNFRSF12A (TNF Receptor Superfamily member 12A). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf12a Products(2)

mRNA	Protein	Name
NM_001161746.1	NP_001155218.1	tumor necrosis factor receptor superfamily member 12A isoform 2 precursor
NM_013749.2	NP_038777.2	tumor necrosis factor receptor superfamily member 12A isoform 1 precursor

Protein Preferred Names

Protein Names

tumor necrosis factor receptor superfamily member 12A

FGF-inducible 14	fibroblast growth factor-inducible immediate-early response protein 14
fibroblast growth factor-regulated protein 2	tweak-receptor
type I transmembrane protein Fn14

Recombinant Tnfrsf12a Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72435	TNFRSF12A Protein, Mouse (HEK293, Fc)	Q9CR75 (E28-W79)	≥95%
HY-P700229AF	Animal-Free TNFRSF12A Protein, Mouse (His)	Q9CR75 (S94-H249)	≥95%

Related Agents

Clinical Phase

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99361	Enavatuzumab	Inhibitor	≥95.0%	Phase 1

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14803	TNFRSF12A Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tnfrsf12a	NCBI	NCBI:51330

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