SAP30BP - SAP30 binding protein Gene

Homo sapiens

Also known as HTRG; HTRP; HCNGP

Gene ID: 29115 | Gene type: protein coding

About SAP30BP

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:75,667,338-75,708,059 (from NCBI)

This gene has 26 transcripts (splice variants) and 223 orthologues. Ubiquitous expression in bone marrow (RPKM 20.7), brain (RPKM 12.2) and 25 other tissues.

Summary

Involved in modulation by host of symbiont transcription; positive regulation of histone deacetylation; and response to virus. Located in intermediate filament Cytoskeleton and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SAP30BP Products(3)

mRNA	Protein	Name
NM_001301839.2	NP_001288768.1	SAP30-binding protein isoform 3
NM_001301855.2	NP_001288784.1	SAP30-binding protein isoform 1
NM_013260.8	NP_037392.1	SAP30-binding protein isoform 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	15496587	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in modulation by host of symbiont transcription	IDA IDA: Inferred from direct assay	21221920	GOA
involved in response to virus	IEP IEP: Inferred from expression pattern	15496587	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	15496587	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SAP30BP Protein Structure

HCNGP

0
100
200
308 a.a.

Protein Preferred Names

Protein Names

SAP30-binding protein

HSV-1 binding

SAP30BP Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SAP30BP	Q9UHR5	PUF60	Homo sapiens	Q9UHX1	Y2H Pooling	16189514
Intra	SAP30BP	Q9UHR5	PUF60	Homo sapiens	Q9UHX1	Validated Y2H	25416956
Intra	SAP30BP	Q9UHR5	PUF60	Homo sapiens	Q9UHX1	Y2H Prey Pooling	25416956
Intra	SAP30BP	Q9UHR5	PUF60	Homo sapiens	Q9UHX1	Y2H	22365833
Intra	SAP30BP	Q9UHR5	PUF60	Homo sapiens	Q9UHX1	Anti Tag CoIP	18255255
Intra	SAP30BP	Q9UHR5	PUF60	Homo sapiens	Q9UHX1	Y2H	18255255
Intra	SAP30BP	Q9UHR5	PUF60	Homo sapiens	Q9UHX1	Y2H Array	25416956
Intra	SAP30BP	Q9UHR5	TFIP11	Homo sapiens	Q9UBB9	Y2H Array	25416956
Intra	SAP30BP	Q9UHR5	TFIP11	Homo sapiens	Q9UBB9	Y2H Array	31515488
Intra	SAP30BP	Q9UHR5	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	25416956
Intra	SAP30BP	Q9UHR5	OGT	Homo sapiens	O15294-3	Y2H Prey Pooling	32296183
Intra	SAP30BP	Q9UHR5	OGT	Homo sapiens	O15294-3	Y2H Array	32296183
Intra	SAP30BP	Q9UHR5	PRKAR1B	Homo sapiens	P31321	Y2H Prey Pooling	32296183
Intra	SAP30BP	Q9UHR5	PRKAR1B	Homo sapiens	P31321	Y2H Array	32296183
Intra	SAP30BP	Q9UHR5	CCNL1	Homo sapiens	Q9UK58	Y2H Prey Pooling	32296183
Intra	SAP30BP	Q9UHR5	CCNL1	Homo sapiens	Q9UK58	Y2H Array	32296183
Intra	SAP30BP	Q9UHR5	CCNL1	Homo sapiens	Q9UK58	Validated Y2H	32296183
Intra	SAP30BP	Q9UHR5	CCNL1	Homo sapiens	Q9UK58	Anti Tag CoIP	33961781
Intra	SAP30BP	Q9UHR5	GOLGA2	Homo sapiens	Q08379	Validated Y2H	25416956
Intra	SAP30BP	Q9UHR5	FHL3	Homo sapiens	Q13643	Y2H Prey Pooling	32296183
Intra	SAP30BP	Q9UHR5	FHL3	Homo sapiens	Q13643	Validated Y2H	25416956
Intra	SAP30BP	Q9UHR5	FHL3	Homo sapiens	Q13643	Y2H Array	32296183
Intra	SAP30BP	Q9UHR5	FHL3	Homo sapiens	Q13643	Y2H Prey Pooling	25416956
Intra	SAP30BP	Q9UHR5	THAP1	Homo sapiens	Q9NVV9	Validated Y2H	25416956
Intra	SAP30BP	Q9UHR5	THAP1	Homo sapiens	Q9NVV9	Y2H Prey Pooling	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Omsk Hemorrhagic Fever

Ohf	Hemorrhagic Fever, Omsk
Ohf - [Omsk Haemorrhagic Fever]	Spring-Fall Haemorrhagic Fever

Alveoli Adenoma

Alveolar Adenoma	Adenoma Of Alveoli
Adenoma Of The Alveoli

Bronchial Benign Neoplasm

Bronchus Neoplasm	Neoplasm Of Bronchus
Bronchial Neoplasms	Bronchial Neoplasm

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12441	SAP30BP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SAP30BP	VGNC	VGNC:45861
Mus musculus	SAP30BP	MGD	MGI:1927479
Felis catus	SAP30BP	VGNC	VGNC:99443
Rattus norvegicus	SAP30BP	RGD	RGD:1565537
Bos taurus	SAP30BP	VGNC	VGNC:34283
Macaca mulatta	SAP30BP	VGNC	VGNC:77142

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