2. Gene
  3. Ccl11 - C-C motif chemokine ligand 11 Gene

Ccl11 - C-C motif chemokine ligand 11 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Scya11

Gene ID: 29397 | Gene type: protein coding

About Ccl11

Summary

Enables chemokine activity. Involved in several processes, including ERK1 and ERK2 cascade; leukocyte chemotaxis; and response to interleukin-13. Located in extracellular space. Used to study allergic rhinitis; asthma; pleurisy; and pneumonia. Biomarker of several diseases, including allergic conjunctivitis; pneumonia; prostatitis; rhinitis; and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in asthma; human immunodeficiency virus infectious disease; hyperglycemia; and multiple sclerosis. Orthologous to several human genes including CCL11 (C-C motif chemokine ligand 11). [provided by Alliance of Genome Resources, Apr 2022]

Ccl11 Products(1)

mRNA Protein Name
NM_019205.2 NP_062078.1 eotaxin precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chemokine activity IDA
IDA: Inferred from direct assay
9458816 RGD
Biological Process GO Annotation Evidence Reference Source
involved in ERK1 and ERK2 cascade IGI
IGI: Inferred from genetic interaction
12413953 RGD
involved in actin filament organization IDA
IDA: Inferred from direct assay
12413953 RGD
involved in chronic inflammatory response IEP
IEP: Inferred from expression pattern
10861753 RGD
involved in eosinophil chemotaxis IDA
IDA: Inferred from direct assay
9458816 RGD
involved in eosinophil chemotaxis IMP
IMP: Inferred from mutant phenotype
9531320 RGD
involved in mast cell chemotaxis IDA
IDA: Inferred from direct assay
12413953 RGD
involved in response to interleukin-13 IEP
IEP: Inferred from expression pattern
15953562 RGD
involved in response to interleukin-4 IEP
IEP: Inferred from expression pattern
11071660 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
9458816 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eotaxin

C-C motif chemokine 11

chemokine (C-C motif) ligand 11

eosinophil chemotactic protein

small inducible cytokine subfamily A11

small-inducible cytokine A11

Recombinant Ccl11 Proteins

Cat. No. Product Name Accession Purity
HY-P71901 CCL11 Protein, Rat P97545 (H24-P97) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99474 Bertilimumab Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N2609 7,4'-Dihydroxyflavone Inhibitor 99.68% Unkown
HY-103361 SB297006 Antagonist 99.88% Unkown
HY-110295 SPL-334 Inhibitor / Unkown
HY-RS02081 CCL11 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-111198 YM-355179 fumarate / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccl11 NCBI NCBI:6356
Mus musculus Ccl11 NCBI NCBI:20292
Macaca mulatta Ccl11 NCBI NCBI:574218