2. Gene
  3. Ccl11 - chemokine (C-C motif) ligand 11 Gene

Ccl11 - chemokine (C-C motif) ligand 11 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Scya11; eotaxin

Gene ID: 20292 | Gene type: protein coding

About Ccl11

Summary

Predicted to enable CCR3 Chemokine Receptor binding activity; chemokine activity; and protein dimerization activity. Involved in several processes, including modulation of age-related behavioral decline; negative regulation of neurogenesis; and positive regulation of angiogenesis. Acts upstream of or within branching involved in mammary gland duct morphogenesis and mammary duct terminal end bud growth. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in embryo; endocardial lining; liver parenchyma; liver vasculature; and yolk sac blood vessel. Human ortholog(s) of this gene implicated in asthma; human immunodeficiency virus infectious disease; hyperglycemia; and multiple sclerosis. Orthologous to several human genes including CCL11 (C-C motif chemokine ligand 11). [provided by Alliance of Genome Resources, Apr 2022]

Ccl11 Products(1)

mRNA Protein Name
NM_011330.3 NP_035460.1 eotaxin precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within branching involved in mammary gland duct morphogenesis IMP
IMP: Inferred from mutant phenotype
10804170 MGI
involved in learning or memory IDA
IDA: Inferred from direct assay
21886162 MGI
acts upstream of or within mammary duct terminal end bud growth IMP
IMP: Inferred from mutant phenotype
10804170 MGI
involved in negative regulation of neurogenesis IDA
IDA: Inferred from direct assay
21886162 MGI
involved in positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
19525930 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eotaxin

C-C motif chemokine 11

eosinophil chemotactic protein

small chemokine (C-C motif) ligand 11

small-inducible cytokine A11

Recombinant Ccl11 Proteins

Cat. No. Product Name Accession Purity
HY-P7160 Eotaxin/CCL11 Protein, Mouse P48298 (H24-P97) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99474 Bertilimumab Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N2609 7,4'-Dihydroxyflavone Inhibitor 99.68% Unkown
HY-103361 SB297006 Antagonist 99.88% Unkown
HY-110295 SPL-334 Inhibitor / Unkown
HY-RS02081 CCL11 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-111198 YM-355179 fumarate / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccl11 NCBI NCBI:6356
Rattus norvegicus Ccl11 NCBI NCBI:29397
Macaca mulatta Ccl11 NCBI NCBI:574218