2. Gene
  3. CCDC137 - coiled-coil domain containing 137 Gene

CCDC137 - coiled-coil domain containing 137 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RaRF

Gene ID: 339230 | Gene type: protein coding

About CCDC137

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:81,666,737-81,673,899 (from NCBI)

This gene has 6 transcripts (splice variants) and 192 orthologues. Ubiquitous expression in skin (RPKM 7.7), lymph node (RPKM 6.5) and 25 other tissues.

Summary

Enables RNA binding activity. Located in chromosome and fibrillar center. [provided by Alliance of Genome Resources, Apr 2022]

CCDC137 Products(1)

mRNA Protein Name
NM_199287.3 NP_954981.1 coiled-coil domain-containing protein 137
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21044950 GOA
Cellular Component GO Annotation Evidence Reference Source
located in chromosome IDA
IDA: Inferred from direct assay
20813266 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coiled-coil domain-containing protein 137

hepatocellular carcinoma related protein 2

CCDC137 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
CCDC137 Q6PK04 TERF2 Homo sapiens Q15554
BiFC
21044950
Intra
CCDC137 Q6PK04 TERF2 Homo sapiens Q15554
Pull Down
21044950
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Familial Thyroid Dyshormonogenesis

Thyroid Dyshormonogenesis

Familial Dyshormonogenetic Goiter
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02029 CCDC137 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CCDC137 VGNC VGNC:26849
Macaca mulatta CCDC137 VGNC VGNC:103795
Mus musculus CCDC137 MGD MGI:1914541
Rattus norvegicus CCDC137 RGD RGD:1591129
Canis familiaris CCDC137 VGNC VGNC:38793
Felis catus CCDC137 VGNC VGNC:60460