BEX5 - brain expressed X-linked 5 Gene

Homo sapiens

Also known as NGFRAP1L1

Gene ID: 340542 | Gene type: protein coding

About BEX5

Cytogenetic location: Xq22.1 Genomic coordinates (GRCh38): X:102,153,712-102,155,977 (from NCBI)

This gene has 3 transcripts (splice variants), 60 orthologues and 3 paralogues. Biased expression in brain (RPKM 24.8), thyroid (RPKM 6.2) and 10 other tissues.

Summary

Predicted to enable signaling receptor binding activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

BEX5 Products(2)

mRNA	Protein	Name
NM_001012978.3	NP_001012996.1	protein BEX5
NM_001159560.2	NP_001153032.1	protein BEX5

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BEX5 Protein Structure

BEX

0
100
111 a.a.

Protein Preferred Names

Protein Names

protein BEX5

BEX family member 5

BEX5 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	BEX5	Q5H9J7	GOLGA8F	Homo sapiens	Q08AF8	Y2H Prey Pooling	25416956
Intra	BEX5	Q5H9J7	MAGEA8	Homo sapiens	P43361	Validated Y2H	25416956
Intra	BEX5	Q5H9J7	MAGEA8	Homo sapiens	P43361	Y2H Array	29892012
Intra	BEX5	Q5H9J7	MAGEA8	Homo sapiens	P43361	Y2H Array	31515488
Intra	BEX5	Q5H9J7	MAGEA8	Homo sapiens	P43361	Y2H Prey Pooling	25416956
Intra	BEX5	Q5H9J7	FKBP1A	Homo sapiens	Q0VDC6	Validated Y2H	32814053
Intra	BEX5	Q5H9J7	FKBP1A	Homo sapiens	Q0VDC6	Y2H Array	32814053
Intra	BEX5	Q5H9J7	FKBP1A	Homo sapiens	Q0VDC6	Y2H Pooling	32814053
Intra	BEX5	Q5H9J7	MORF4L1	Homo sapiens	Q9UBU8-2	Validated Y2H	32296183
Intra	BEX5	Q5H9J7	GTF3C3	Homo sapiens	Q9Y5Q9	Validated Y2H	32814053
Intra	BEX5	Q5H9J7	GTF3C3	Homo sapiens	Q9Y5Q9	Y2H Array	32814053
Intra	BEX5	Q5H9J7	GTF3C3	Homo sapiens	Q9Y5Q9	Y2H Pooling	32814053
Intra	BEX5	Q5H9J7	PACRGL	Homo sapiens	Q8N7B6-2	Validated Y2H	32296183
Intra	BEX5	Q5H9J7	DMWD	Homo sapiens	G5E9A7	Validated Y2H	32814053
Intra	BEX5	Q5H9J7	DMWD	Homo sapiens	G5E9A7	Y2H Pooling	32814053
Intra	BEX5	Q5H9J7	DMWD	Homo sapiens	G5E9A7	Y2H Array	32814053
Intra	BEX5	Q5H9J7	GNG13	Homo sapiens	Q9P2W3	Validated Y2H	32296183
Intra	BEX5	Q5H9J7	FOXD4L3	Homo sapiens	Q6VB84	Validated Y2H	32296183
Intra	BEX5	Q5H9J7	COPS7B	Homo sapiens	Q9H9Q2	Validated Y2H	32296183
Intra	BEX5	Q5H9J7	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
Intra	BEX5	Q5H9J7	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
Intra	BEX5	Q5H9J7	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
Intra	BEX5	Q5H9J7	GSN	Homo sapiens	P06396	Validated Y2H	32814053
Intra	BEX5	Q5H9J7	GSN	Homo sapiens	P06396	Y2H Array	32814053
Intra	BEX5	Q5H9J7	GSN	Homo sapiens	P06396	Y2H Pooling	32814053
Intra	BEX5	Q5H9J7	SPRED1	Homo sapiens	Q7Z699	Validated Y2H	32814053
Intra	BEX5	Q5H9J7	SPRED1	Homo sapiens	Q7Z699	Y2H Pooling	32814053
Intra	BEX5	Q5H9J7	SPRED1	Homo sapiens	Q7Z699	Y2H Array	32814053
Intra	BEX5	Q5H9J7	EMILIN1	Homo sapiens	Q9Y6C2	Y2H Array	25416956
Intra	BEX5	Q5H9J7	EMILIN1	Homo sapiens	Q9Y6C2	Y2H Prey Pooling	25416956
Intra	BEX5	Q5H9J7	EMILIN1	Homo sapiens	Q9Y6C2	Validated Y2H	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Childhood Supratentorial Ependymoma

Paediatric Cerebral Ependymoma	Paediatric Supratentorial Ependymoblastoma
Paediatric Supratentorial Ependymoma	Pediatric Cerebral Ependymoma
Pediatric Supratentorial Ependymoblastoma	Pediatric Supratentorial Ependymoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01484	BEX5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	BEX5	VGNC	VGNC:50553
Rattus norvegicus	BEX5	RGD	RGD:6488322
Canis familiaris	BEX5	VGNC	VGNC:54663

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