2. Gene
  3. YPEL2 - yippee like 2 Gene

YPEL2 - yippee like 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FKSG4

Gene ID: 388403 | Gene type: protein coding

About YPEL2

Cytogenetic location: 17q22 Genomic coordinates (GRCh38): 17:59,331,655-59,401,729 (from NCBI)

This gene has 6 transcripts (splice variants), 175 orthologues and 10 paralogues. Ubiquitous expression in fat (RPKM 5.3), bone marrow (RPKM 5.1) and 25 other tissues.

Summary

Predicted to enable metal ion binding activity. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

YPEL2 Products(1)

mRNA Protein Name
NM_001005404.4 NP_001005404.1 protein yippee-like 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

YPEL2 Protein Structure

Yippee-Mis18

Yippee-Mis18: Yippee zinc-binding/DNA-binding /Mis18, centromere assembly (20 - 111)

  • 0
  • 100
  • 119 a.a.
Protein Preferred Names Protein Names

protein yippee-like 2

DiGeorge syndrome-related protein

YPEL2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
YPEL2 Q96QA6 SH2D4A Homo sapiens Q9H788
Validated Y2H
32296183
Intra
YPEL2 Q96QA6 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
YPEL2 Q96QA6 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Retinitis Pigmentosa 17

RP17

Retinitis Pigmentosa-17

Retinitis Pigmentosa, Type 17
Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15931 YPEL2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus YPEL2 MGD MGI:1925114
Bos taurus YPEL2 VGNC VGNC:37035
Macaca mulatta YPEL2 VGNC VGNC:104676
Rattus norvegicus YPEL2 RGD RGD:1311564
Canis familiaris YPEL2 VGNC VGNC:48498
Felis catus YPEL2 VGNC VGNC:99576