VMAC - vimentin type intermediate filament associated coiled-coil protein Gene

Homo sapiens

Gene ID: 400673 | Gene type: protein coding

About VMAC

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:5,904,872-5,910,853 (from NCBI)

This gene has 1 transcript (splice variant) and 127 orthologues. Ubiquitous expression in prostate (RPKM 4.1), spleen (RPKM 3.5) and 25 other tissues.

Summary

Predicted to be located in cytoplasm. Predicted to be active in type III intermediate filament. [provided by Alliance of Genome Resources, Apr 2022]

VMAC Products(1)

mRNA	Protein	Name
NM_001017921.4	NP_001017921.1	vimentin-type intermediate filament-associated coiled-coil protein

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

vimentin-type intermediate filament-associated coiled-coil protein

vimentin-type IF-associated coiled-coil protein

VMAC Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	VMAC	Q2NL98	BANP	Homo sapiens	Q8N9N5-2	Anti Tag CoIP	28514442
Intra	VMAC	Q2NL98	BANP	Homo sapiens	Q8N9N5-2	Validated Y2H	32296183
Intra	VMAC	Q2NL98	LMO3	Homo sapiens	Q8TAP4-4	Validated Y2H	32296183
Intra	VMAC	Q2NL98	SAXO4	Homo sapiens	Q7Z5V6-2	Validated Y2H	32296183
Intra	VMAC	Q2NL98	KANK2	Homo sapiens	Q63ZY3	Validated Y2H	32296183
Intra	VMAC	Q2NL98	ZNF326	Homo sapiens	Q5BKZ1	Validated Y2H	32296183
Intra	VMAC	Q2NL98	SDK2	Homo sapiens	Q58EX2	Validated Y2H	32296183
Intra	VMAC	Q2NL98	NGLY1	Homo sapiens	Q96IV0	Validated Y2H	32296183
Intra	VMAC	Q2NL98	LNX1	Homo sapiens	Q8TBB1	Validated Y2H	32296183
Intra	VMAC	Q2NL98	SPG21	Homo sapiens	Q9NZD8	Validated Y2H	32296183
Intra	VMAC	Q2NL98	SCNM1	Homo sapiens	Q9BWG6	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Tick Infestation

Tick Infestations

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15663	VMAC Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	VMAC	MGD	MGI:2146912
Bos taurus	VMAC	VGNC	VGNC:97326
Canis familiaris	VMAC	VGNC	VGNC:97229
Rattus norvegicus	VMAC	RGD	RGD:1303340
Others	VMAC	NCBI

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