1. Gene
  2. Gfral - GDNF family receptor alpha like Gene

Gfral - GDNF family receptor alpha like Gene

Rattus norvegicus

Also known as RGD1565220

Gene ID: 501023 | Gene type: protein coding

About Gfral

Summary

Predicted to enable glial cell-derived neurotrophic factor receptor activity and receptor tyrosine kinase binding activity. Predicted to be involved in several processes, including glial cell-derived neurotrophic factor receptor signaling pathway; positive regulation of intracellular signal transduction; and reduction of food intake in response to dietary excess. Predicted to act upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of neuron apoptotic process; and stress-activated protein kinase signaling cascade. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Orthologous to human GFRAL (GDNF family receptor alpha like). [provided by Alliance of Genome Resources, Apr 2022]

Gfral Products(3)

mRNA Protein Name
NM_001191998.2 NP_001178927.1 GDNF family receptor alpha-like isoform 3 precursor
NM_001401789.1 NP_001388718.1 GDNF family receptor alpha-like isoform 1
NM_001401790.1 NP_001388719.1 GDNF family receptor alpha-like isoform 2 precursor
Protein Preferred Names Protein Names

GDNF family receptor alpha-like

Orthologs Information

Species Symbol Source ID
Homo sapiens Gfral NCBI NCBI:389400
Macaca fascicularis Gfral NCBI NCBI:102126381
Mus musculus Gfral NCBI NCBI:404194