1. Gene
  2. SERPINE1 - serpin family E member 1 Gene

SERPINE1 - serpin family E member 1 Gene

Homo sapiens

Also known as PAI; PAI1; PAI-1; PLANH1

Gene ID: 5054 | Gene type: protein coding

About SERPINE1

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:101,127,104-101,139,247 (from NCBI)

This gene has 1 transcript (splice variant), 186 orthologues, 36 paralogues and is associated with 2 phenotypes. Biased expression in gall bladder (RPKM 208.8), placenta (RPKM 164.7) and 7 other tissues.

Summary

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate Antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq, Aug 2020]

SERPINE1 Products(13)

mRNA Protein Name
NM_001386458.1 NP_001373387.1 plasminogen activator inhibitor 1 isoform 5 precursor
NM_001386461.1 NP_001373390.1 plasminogen activator inhibitor 1 isoform 7 precursor
NM_001386462.1 NP_001373391.1 plasminogen activator inhibitor 1 isoform 8
NM_001386466.1 NP_001373395.1 plasminogen activator inhibitor 1 isoform 12 precursor
NM_000602.5 NP_000593.1 plasminogen activator inhibitor 1 isoform 2 precursor
NM_001386463.1 NP_001373392.1 plasminogen activator inhibitor 1 isoform 9 precursor
NM_001386464.1 NP_001373393.1 plasminogen activator inhibitor 1 isoform 10 precursor
NM_001165413.2
NM_001386459.1 NP_001373388.1 plasminogen activator inhibitor 1 isoform 6 precursor
NM_001386465.1 NP_001373394.1 plasminogen activator inhibitor 1 isoform 11 precursor
NM_001386457.1 NP_001373386.1 plasminogen activator inhibitor 1 isoform 4 precursor
NM_001386456.1 NP_001373385.1 plasminogen activator inhibitor 1 isoform 3
NM_001386460.1 NP_001373389.1 plasminogen activator inhibitor 1 isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protease binding IPI
IPI: Inferred from physical interaction
2503541 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16272158 GOA
enables serine-type endopeptidase inhibitor activity IDA
IDA: Inferred from direct assay
1695900 GOA
enables signaling receptor binding IPI
IPI: Inferred from physical interaction
8626514 GOA
Biological Process GO Annotation Evidence Reference Source
involved in angiogenesis IEP
IEP: Inferred from expression pattern
11866539 GOA
involved in cellular response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
19916862 GOA
involved in defense response to Gram-negative bacterium IGI
IGI: Inferred from genetic interaction
17032919 GOA
involved in dentinogenesis IDA
IDA: Inferred from direct assay
27046084 GOA
involved in negative regulation of cell adhesion mediated by integrin IDA
IDA: Inferred from direct assay
8837777 GOA
involved in negative regulation of cell migration IDA
IDA: Inferred from direct assay
10902815 GOA
involved in negative regulation of endopeptidase activity IDA
IDA: Inferred from direct assay
1695900 GOA
involved in negative regulation of endothelial cell apoptotic process IMP
IMP: Inferred from mutant phenotype
18835034 GOA
involved in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IMP
IMP: Inferred from mutant phenotype
18835034 GOA
involved in negative regulation of fibrinolysis IDA
IDA: Inferred from direct assay
2503541 GOA
involved in negative regulation of plasminogen activation IDA
IDA: Inferred from direct assay
8508955 GOA
involved in negative regulation of plasminogen activation IMP
IMP: Inferred from mutant phenotype
18835034 GOA
involved in negative regulation of smooth muscle cell migration IDA
IDA: Inferred from direct assay
8837777 GOA
involved in negative regulation of smooth muscle cell-matrix adhesion IDA
IDA: Inferred from direct assay
8837777 GOA
involved in negative regulation of vascular wound healing IGI
IGI: Inferred from genetic interaction
9386191 GOA
involved in positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
18835034 GOA
involved in positive regulation of blood coagulation IMP
IMP: Inferred from mutant phenotype
9207454 GOA
involved in positive regulation of inflammatory response IGI
IGI: Inferred from genetic interaction
17032919 GOA
involved in positive regulation of interleukin-8 production IMP
IMP: Inferred from mutant phenotype
19916862 GOA
involved in positive regulation of leukotriene production involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
19916862 GOA
involved in positive regulation of monocyte chemotaxis IMP
IMP: Inferred from mutant phenotype
19916862 GOA
involved in positive regulation of odontoblast differentiation IDA
IDA: Inferred from direct assay
27046084 GOA
involved in positive regulation of receptor-mediated endocytosis IDA
IDA: Inferred from direct assay
8626514 GOA
involved in regulation of signaling receptor activity IDA
IDA: Inferred from direct assay
8837777 GOA
involved in replicative senescence IMP
IMP: Inferred from mutant phenotype
16862142 GOA
Cellular Component GO Annotation Evidence Reference Source
located in collagen-containing extracellular matrix IDA
IDA: Inferred from direct assay
1632457 GOA
located in extracellular exosome IDA
IDA: Inferred from direct assay
21276792 GOA
located in extracellular region IDA
IDA: Inferred from direct assay
9386191 GOA
located in extracellular space IDA
IDA: Inferred from direct assay
1695900 GOA
part of peptidase inhibitor complex IPI
IPI: Inferred from physical interaction
12808446 GOA
part of serine protease inhibitor complex IPI
IPI: Inferred from physical interaction
21199867 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SERPINE1 Protein Structure

Serpin

Serpin: Serpin (serine protease inhibitor) (36 - 402)

  • 0
  • 100
  • 200
  • 300
  • 402 a.a.
Protein Preferred Names Protein Names

plasminogen activator inhibitor 1

endothelial plasminogen activator inhibitor

serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

serpin E1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

SERPINE1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
SERPINE1 P05121 UBQLN1 Homo sapiens Q9UMX0-2
Y2H Array
25416956
Intra
SERPINE1 P05121 HSD17B11 Homo sapiens Q8NBQ5
Validated Y2H
32296183
Intra
SERPINE1 P05121 HSD17B11 Homo sapiens Q8NBQ5
Y2H Array
32296183
Intra
SERPINE1 P05121 HSD17B11 Homo sapiens Q8NBQ5
Y2H Prey Pooling
32296183
Intra
SERPINE1 P05121 TMEM237 Homo sapiens Q96Q45-2
Validated Y2H
32296183
Intra
SERPINE1 P05121 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra
SERPINE1 P05121 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra
SERPINE1 P05121 SGTA Homo sapiens O43765
Y2H Prey Pooling
32296183
Intra
SERPINE1 P05121 SGTA Homo sapiens O43765
Y2H Array
25416956
Intra
SERPINE1 P05121 SGTA Homo sapiens O43765
Y2H Array
32296183
Intra
SERPINE1 P05121 SGTA Homo sapiens O43765
Y2H Prey Pooling
25416956
Intra
SERPINE1 P05121 PLAU Homo sapiens P00749
Comigration in Gel
22449964
Intra
SERPINE1 P05121 UBQLN1 Homo sapiens Q9UMX0
Y2H Prey Pooling
25416956
Intra
SERPINE1 P05121 UBQLN1 Homo sapiens Q9UMX0
Y2H Array
25416956
Intra
SERPINE1 P05121 SGTB Homo sapiens Q96EQ0
Y2H Array
32296183
Intra
SERPINE1 P05121 SGTB Homo sapiens Q96EQ0
Y2H Prey Pooling
25416956
Intra
SERPINE1 P05121 SGTB Homo sapiens Q96EQ0
Y2H Prey Pooling
32296183
Intra
SERPINE1 P05121 SGTB Homo sapiens Q96EQ0
Validated Y2H
25416956
Intra
SERPINE1 P05121 SGTB Homo sapiens Q96EQ0
Validated Y2H
32296183
Intra
SERPINE1 P05121 SGTB Homo sapiens Q96EQ0
Y2H Array
25416956
Intra
SERPINE1 P05121 PITX1 Homo sapiens P78337
Validated Y2H
32296183
Intra
SERPINE1 P05121 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
Intra
SERPINE1 P05121 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
Intra
SERPINE1 P05121 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
Intra
SERPINE1 P05121 ORM1 Homo sapiens P02763
FACS
16272158
Intra
SERPINE1 P05121 ORM1 Homo sapiens P02763
ELISA
16272158
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant SERPINE1 Proteins

Cat. No. Product Name Accession Purity
HY-P71077 Serpin E1 Protein, Human (HEK293, His) P05121-1 (V24-P402) ≥95%

Related Diseases

Diseases Alias
Disseminated Intravascular Coagulation

Defibrination Syndrome

Dic

Diffuse Or Disseminated Intravascular Coagulation

Fibrinolytic Purpura

Consumption Coagulopathy

Diffuse Intravascular Coagulation

Dic - [Disseminated Intravascular Coagulation]

Disseminated Intravascular Coagulopathy

Fibrinolysis Nos

Thrombolytic Purpura

Complete Plasminogen Activator Inhibitor 1 Deficiency

Congenital Plasminogen Activator Inhibitor Type 1 Deficiency

Complete Pai-1 Deficiency

Homozygous Pai-1 Deficiency

Hyperfibrinolysis Due To Pai1 Deficiency

Pai-1 Deficiency

Pai-1d

Pai1 Deficiency

Plasminogen Activator Inhibitor Type 1 Deficiency

Plasminogen Inhibitor-1 Deficiency

Quantitative Pai-1 Deficiency

Congenital Pai-1 Deficiency

Congenital Pai-1 - [Plasminogen Activator Inhibitor Type 1] Deficiency

Peyronie'S Disease

Induratio Penis Plastica

Peyronie Disease

Peyronies Disease

Peyronie'S Fibromatosis

Penile Induration

Balanitis Xerotica Obliterans

Blood Coagulation Disease

Blood Coagulation Disorders

Coagulation Protein Disease

Inherited Blood Coagulation Disease

Postpartum Coagulation Defect

Postpartum Coagulation Defect With Delivery

Coagulation Protein Disorders

Puerperal Coagulopathy

Myocardial Infarction

Heart Attack

Myocardial Infarction, Susceptibility To

Myocardial Infarction 1

Myocardial Infarction, Protection Against

Myocardial Infarction, Decreased Susceptibility To

Myocardial Infarction, Decreased

Myocardial Infarct

MCI1

Premature Myocardial Infarction

Myocardial Infarction, Susceptibility To, Type 1

Fibrinolytic Defect
Dysbaric Osteonecrosis

Caisson Disease Of Bone

Don

Livedoid Vasculitis

Livedoid Vasculopathy

Livedo Reticularis With Summer Ulcerations

Livedo Vasculitis

Livedo Reticularis With Winter Ulcerations

Segmental Hyalinizing Vasculopathy

Milian Atrophie Blanche

Segmental Hyalinizing Vasculitis

Livedo Reticularis With Summer Ulceration

Ureteral Disease

Ureteral Diseases

Ureteral Disorders

Disorder Of Ureter

Kidney Disease

Renal Failure

Kidney Failure

Kidney Diseases

Nephropathy

Abnormality Of The Kidney

Impaired Renal Function Disease

Renal Anomaly

Kidney Dysfunction

Renal Disease

Nephropathies

Renal Failure Adverse Event

Abnormal Renal Function

Venous Insufficiency

Peripheral Venous Insufficiency

Lipid Metabolism Disorder

Dyslipidemia

Disorder Of Fatty Acid Metabolism

Lipid Metabolism Disorders

Fatty Acid Metabolism Disorder

Disorder Of Lipid Metabolism

Abnormality Of Lipid Metabolism

Lipid Metabolism, Inborn Errors

Dyslipidemias

Disorders Of Lipid Metabolism

Congenital Disorders Of Lipid Metabolism

Inherited Disorders Of Lipid Metabolism

Diabetic Angiopathy

Diabetic Angiopathies

Diabetic Peripheral Angiopathy

Diabetic Vascular Disorder

Dic In Newborn

Disseminated Intravascular Coagulation In Newborn

Hyperinsulinism

Hyperinsulinemia

Coronary Thrombosis

Coronary Artery Thrombosis

Hemolytic-Uremic Syndrome

Hemolytic Uremic Syndrome

Haemolytic-Uraemic Syndrome

Hus

Acute Renal Failure, Thrombocytopenia, And Microangiopathic Hemolytic Anemia Associated With Distorted Erythrocytes

Typical Haemolytic Uraemic Syndrome

Gasser Syndrome

Hus - [Haemolytic Uraemic Syndrome]

Microvascular Complications Of Diabetes 5

Diabetic Retinopathy

Microvascular Complications Of Diabetes, Susceptibility To, 5

MVCD5

Retinopathy, Diabetic

Diabetic Nephropathy

Retinopathy, Diabetic, Susceptibility To

Retinal Abnormality - Diabetes-Related

Patent Foramen Ovale

Atrial Septal Defect Within Oval Fossa

Foramen Ovale Patent

Ostium Secundum Atrial Septal Defect

Atrial Septal Defect, Ostium Secundum Type

Foramen Ovale, Patent

Defect, Patent Or Persistent, Ostium Secundum

Ostium Secundum Type Atrial Septal Defect

Persistent Ostium Secundum

Asd Ostium Secundum Type

Ostium Secundum Asd

Osasd

Asd, Ostium Secundum Type

Pfo - [Patent Foramen Ovale]

Open Foramen Ovale

Open Oval Foramen

Persistent Foramen Ovale

Secundum Atrial Septal Defect

Hyperuricemia

Blood Urate Raized

Uricacidemia

Hypertriglyceridemia 1

Hypertriglyceridemia

Hypertriglyceridemia, Familial

Hypertriglyceridemia, Susceptibility To

HYTG1

FHTR

Hypertriglyceridemias Familial

Acquired Metabolic Disease
Coronary Stenosis

Coronary Artery Stenosis

Arteriosclerosis

Arteriosclerotic Vascular Disease

Intracranial Arteriosclerosis
Thrombocytopenia

Low Platelet Count

Low Platelets

Decreased Platelets

Platelet Dysfunction Nos

Yellow Fever

Urban Yellow Fever

Jungle Yellow Fever

Sylvatic Yellow Fever

Yf

Yellow Fever, Sylvan

Bronze John

Yellow Jack

Yf- [Yellow Fever]

Febris Flava

Cardiovascular System Disease

Abnormality Of The Cardiovascular System

Disease Of Subdivision Of Hemolymphoid System

Disorder Of Cardiovascular System

Cardiovascular Diseases

Cardiovascular Disease

Protein C Deficiency

Hereditary Thrombophilia Due To Protein C Deficiency

Proc Deficiency

Congenital Thrombotic Disease, Due To Protein C Deficiency

Malaria

Malaria, Susceptibility To

Malaria, Resistance To

Malaria, Cerebral

Cerebral Malaria

Malaria, Severe, Susceptibility To

Malaria, Severe, Resistance To

Malaria, Cerebral, Susceptibility To

Induced Malaria

Malaria, Vivax, Protection Against

Malaria, Severe

Malaria, Cerebral, Reduced Risk Of

Malaria, Protection Against

Resistance To Malaria Due To G6pd Deficiency

Malaria Due To G6pd Deficiency

Malarial Encephalitis

CM

Malaria Cerebral

Susceptibility To Malaria

Acute Pernicious Fever

Aestivo-Autumnal Fever

Aestivo Autumnal Malaria

Chagres Fever

Continued Malaria Fever

Estivo-Autumnal Fever

Estivo-Autumnal Malaria

Estivo-Autumnal Malarial Fever

Falciparum Fever

Malignant Tertian Fever

Malignant Tertian Malaria

Pernicious Intermittent Fever

Pernicious Malaria

Quotidian Malaria

Subtertian Fever

Subtertian Malaria Fever

Subtertian Malignant Tertian Malaria

Tropical Malaria

Algid Malaria

Bilious Haemoglobinuric Fever

Black Water Fever

Blackwater Fever

Malarial Blackwater Fever

Severe Malarial Falciparum

West African Fever

Malarial Haematinuria

Haemoglobinuric Fever

Haemoglobinuric Malaria

Severe Plasmodium Falciparum Malaria

Malarial Haemoglobinuria

Malarial Haematuria

Falciparum Malaria [Malignant Tertian]

Malaria Tropica

Malarial Shock

Chagres Virus Disease

Malignant Malaria

Mtm - [Malignant Tertian Malaria]

Tm -[Malignant Tertian Malaria]

Panama Fever

St - [Subtertian Malaria]

Malarial Quotidian

Benign Tertian Malaria

Tertian Ague

Vivax Fever

Plasmodium Vivax Malaria Nos

Btm - [Benign Tertian Malaria]

Bt - [Benign Tertian Malaria]

Vivax Malaria

Benign Tertian Vivax Malaria

Tertian Malaria

Quartan Malaria

Quartan Ague

Quartan Fever

Plasmodium Malariae Malaria Nos

Quartan Malarial

Malaria By Plasmodium Malariae

Malariae Malaria

Ovale Tertian Malaria

Plasmodium Ovale Fever

Malaria Fever By Plasmodium Ovale

Ovale Malaria

Malaria By Plasmodium Ovale

Malarial Ovale

Marsh Fever

Remittent Congestive Fever

Coastal Fever

Remittent Gastric Fever

Miasmatic Fever

Congestive Remittent Fever

Intermittent Fever

Jungle Fever

Paludism

Cameroon Fever

Ague

Corsican Fever

Intermittent Bilious Fever

Disease Due To Plasmodiidae

Malarial Fever

Plasmodiosis

Remittent Fever

Roman Fever

Malaria Fever Nos

Malaria Nos

Paludal Fever

Clinically Diagnosed Malaria

Clinically Diagnosed Malaria Without Parasitological Confirmation

Congestive Fever

Malarial Cachexia

Marsh Cachexia

Paludal Cachexia

Recurrent Malaria

Remittent Malaria

Plasminogen Deficiency, Type I

Hypoplasminogenemia

Dysplasminogenemia

Plasminogen Deficiency Type I

Congenital Plasminogen Deficiency

Ligneous Conjunctivitis

Type 1 Plasminogen Deficiency

Plasminogen Deficiency Type 1

Plasminogen Deficiency

PLGD

Plasminogen Deficiency Type Ii

Deficiency, Plasminogen, Type I

Retinal Vein Occlusion

Occlusion, Of Retinal Vein

Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic

Pre-Eclampsia

Preeclampsia

Gestational Hypertension

Hypertension Induced By Pregnancy

Pre-Eclamptic Toxaemia

Pregnancy Associated Hypertension

Proteinuric Hypertension Of Pregnancy

Hypertension, Pregnancy-Induced, Susceptibility To

Preeclampsia/Eclampsia

Pregnancy Toxemia

Toxaemia Of Pregnancy

Gestational Proteinuric Hypertension

Pregnancy-Induced Hypertension

Toxemia Of Pregnancy

Preeclampsia, Susceptibility To

Transient Hypertension Of Pregnancy

Gestational [Pregnancy-Induced] Hypertension Without Significant Proteinuria

Gestational Hypertension Nos

Mild Proteinuric Hypertension Of Pregnancy

Pih - [Pregnancy-Induced Hypertension]

Pregnancy-Induced Hypertension Nos

Gestational [Pregnancy-Induced] Hypertension With Significant Proteinuria

Pe - [Pre-Eclampsia]

Pre-Eclampsia Nos

Pre-Eclamptic Nos

Pregnancy Pre-Eclampsia

Puerperal Pre-Eclampsia

Pre-Eclampsia Toxaemia

Toxaemia In Pregnancy

Pet - [Pre-Eclamptic Toxaemia]

Maternal Toxaemia

Carotid Artery Thrombosis
Hypothyroidism

Thyroid Diseases

Thyroid Deficiency

Thyroid Insufficiency

Dysfunction Thyroid

Thyroid Disease

Thyroid Dysfunction

Factor Xiii Deficiency

Hereditary Factor Xiii Deficiency Disease

Deficiency, Laki-Lorand Factor

Congenital Factor Xiii Deficiency

Fibrin Stabilizing Factor Deficiency

Deficiency, Factor Xiii

Factor Xiii Deficiency Disease

Deficiency Of Factor Xiii

Fibrin-Stabilizing Factor Deficiency

Factor Xiii Deficiency, Congenital

Post-Thrombotic Syndrome

Postphlebitic Syndrome

Postthrombotic Syndrome

Postphlebetic Syndrome With Inflammation

Postphlebetic Syndrome With Ulcer

Postphlebetic Syndrome With Ulcer And Inflammation

Venous Stress Disorder

Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Obesity , Susceptibility To

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis

Breast Cancer

Breast Carcinoma

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Male Breast Cancer

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Hellp Syndrome

Hemolysis, Elevated Liver Enzymes, Lowered Platelets

Hemolysis, Elevated Liver Enzymes, Low Platelets In Pregnancy

Hemolysis-Elevated Liver Enzymes-Low Platelets Syndrome

Hellp - [Syndrome Of Haemolysis, Elevated Liver Enzymes And Low Platelet]

Haemolysis-Elevated Liver Enzymes-Low Platelet Count Syndrome

Intermittent Claudication

Charcot'S Syndrome

Amyotrophic Lateral Sclerosis

Thrombosis

Thrombosis Of Blood Vessel

Aortic Aneurysm

Aortic Rupture

Thoracoabdominal Aortic Aneurysm, Ruptured

Ruptured Aortic Aneurysm

Aortic Aneurysms

Aortic Aneurysm Without Mention Of Rupture Nos

Ruptured Abdominal Aortic Aneurysm

Aortic Aneurysm, Ruptured

Ruptured Thoracic Aortic Aneurysm

Trochlear Nerve Disease

Trochlear Nerve Diseases

Disorder Of Trochlear Nerve

Superior Oblique Muscle Innervation Disorder

Trochlear Nerve Disorder

Fourth Cranial Nerve Paresis

Osteoporosis

Postmenopausal Osteoporosis

Osteoporosis, Postmenopausal

Bone Mineral Density Quantitative Trait Locus

Bmnd

Osteoporosis, Involutional

Osteoporosis, Susceptibility To

Osteoporosis, Postmenopausal, Susceptibility

Bone Mineral Density Variation Qtl, Osteoporosis

OSTEOP

Involutional Osteoporosis

Senile Osteoporosis

Osteoporosis Postmenopausal

Bone Mineral Density, Quantitative Trait Locus

Osteoporosis, Senile

Idiopathic Osteoporosis

Bone Rarefaction Nos

Type 1 Osteoporosis

Lipoprotein Quantitative Trait Locus

Coronary Artery Disease

Coronary Artery Disease, Susceptibility To

Coronary Artery Anomaly

Myocardial Ischemia

Congenital Anomaly Of Coronary Artery

Coronary Arteriosclerosis

Coronary Disease

Coronary Heart Disease

Coronary Artery Disorder

LPAQTL

Lpa Deficiency, Congenital

Coronary Artery Abnormality

Coronary Artery Anomaly, Congenital

Chd

Coronary Syndrome

Congenital Malformations Of Coronary Vessels

Malformation Of Coronary Vessels

Congenital Coronary Artery Anomaly

Congenital Coronary Artery Deformity

Congenital Coronary Artery Disorder

Abnormal Coronary Artery

Congenital Coronary Artery Malposition

Congenital Coronary Disease

Congenital Anomaly Of Coronary Arteries

Alpha-2-Plasmin Inhibitor Deficiency

Plasmin Inhibitor Deficiency

Antiplasmin Deficiency

Antiplasmin Defiency

Anti-Plasmin Deficiency, Congenital

Antiplasmin Deficiency, Congenital

Congenital Alpha2-Antiplasmin Deficiency

APLID

Congenital Alpha2 Antiplasmin Deficiency

Renal Fibrosis
Stroke, Ischemic

Cerebral Infarction

Stroke

Ischemic Stroke

Cerebrovascular Accident

Cerebral Infarction, Susceptibility To

Stroke, Ischemic, Susceptibility To

Cerebral Infarct

Ischemic Stroke, Susceptibility To

Stroke, Susceptibility To

Cva - Cerebral Infarction

ISCHSTR

Ischemic Cerebrovascular Accident

Thrombophilia

Hypercoagulability State

Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

Medulloadrenal Hyperfunction
Obstructive Nephropathy

Con

Congenital Obstructive Nephropathy

Nephropathy Obstructive

Malignant Secondary Hypertension
Fibrosarcoma

Neoplasms, Fibrous Tissue

Fibrocytic Tumor

Fibrosarcoma Of Soft Tissue

Fibrous Tissue Neoplasm

Pneumoconiosis

Pneumoconioses

Silicosis Nos

Complicated Silicosis

Fibrosis Of Lung With Silicosis

Nodular Silicosis

Pneumoconiosis Due To Silica

Silicotic Fibrosis Of Lung

Simple Silicosis

Silicatosis

Silicotic Lung Fibrosis

Pneumoconiosis Due To Talc

Pulmonary Talcosis

Talc Lung Disease

Talc Pneumoconiosis

Talc Workers' Pneumoconiosis

Talcosis

Fibrosis Of Lung Due To Talc

Asbestos Pneumoconiosis

Amianthosis

Asbestosis

Lung Fibrosis With Asbestosis

Pulmonary Asbestosis

Osteonecrosis

Bone Necrosis

Avascular Necrosis Of Bone

Aseptic Necrosis

Necrosis Of Bone Nos

Aseptic Osteonecrosis

Aseptic Necrosis Of Bone, Site Unspecified

Aseptic Or Avascular Bone Necrosis

Aseptic Necrosis Of Bone

Necrotic Bone

Necrotizing Bone

Spontaneous Osteonecrosis

Osteoradionecrosis

Malignant Renovascular Hypertension

Secondary Malignant Renovascular Hypertension

Central Serous Chorioretinopathy

Central Serous Chorioretinopathy After Bone Marrow Transplantation

Central Serous Choroidopathy

Cscr

Central Serous Retinopathy

Central Serous Choroidoretinopathy

Legg-Calve-Perthes Disease

Perthes Disease

LCPD

Coxa Plana

Legg-Perthes Disease

Juvenile Osteochondrosis Of Hip And Pelvis

Pseudocoxalgia

Lcp

Calve - Perthes' Disease

Juvenile Osteochond-Hip/Pelvis

Juvenile Osteochondrosis Of Hip And/Or Pelvis

Legg-Calve-Perthes Symptom

Osteochondrosis Of Legg-Calve-Perthes

Perthe'S Disease

Legg-Calve-Perthes Syndrome

Osteochondritis Deformans

Legg-Calvé-Perthes Disease

Calve-Perthes Disease

Aseptic Necrosis Of The Capital Femoral Epiphysis

Osteochondrosis Of The Capital Femoral Epiphysis

Legg-Calvé-Perthes Syndrome

Avascular Necrosis Of The Capital Femoral Epiphysis

Premature Ovarian Failure 19

POF19

Primary Ovarian Insufficiency 19

Poi19

Ovarian Failure, Premature, Type 19

Thrombophilia Due To Activated Protein C Resistance

Activated Protein C Resistance

Apc Resistance

THPH2

Thrombophilia Due To Deficiency Of Activated Protein C Cofactor

Proc Cofactor Deficiency

Pccf Deficiency

Thrombophilia V

Thrombophilia, Susceptibility To, Due To Factor V Leiden

Thrombophilia Due To Factor V Leiden

Thrombophilia 2 Due To Activated Protein C Resistance

Thrombophilia, Susceptibility To, Due To Activated Protein C Resistance

Pulmonary Embolism

Pulmonary Artery Embolism

Pulmonary Embolus

Pulmonary Emboli

Hyperhomocysteinemia
Hypertension, Essential

Essential Hypertension

Hypertension

High Blood Pressure

Hypertension, Essential, Susceptibility To

Hypertensive Disease

Primary Hypertension

EHT

Hypertension, Salt-Sensitive Essential, Susceptibility To

Hyperpiesia

Idiopathic Hypertension

Hypertensive Disorder

Hypertension, Essential, Susceptibility To, 3

Hypertension, Essential 3

Hypertension, Essential, Salt-Sensitive

Hypertension, Essential, Susceptibility To, 6

Hypertension, Essential 6

Hypertension, Salt-Sensitive Essential

Hypertension, Susceptibility To

Hypertension, Essential, Susceptibility To, 4

Hypertension, Essential 4

Hypertension, Essential, Susceptibility To, 2

Hypertension, Essential 2

Hypertension, Essential, Susceptibility To, 1

Hypertension, Essential 1

Hypertension, Essential, Susceptibility To, 5

Hypertension, Essential 5

Htn

Vascular Hypertensive Disorder

Systemic Primary Arterial Hypertension

Hbp - [High Blood Pressure]

Systemic Arterial Hypertensive Disorder

Elevated Blood Pressure

Arterial Hypertension Nos

Hypertension Nos

Benign Hypertension

Systemic Arterial Hypertension

Systemic Hypertension

Artery Htn

Benign Htn

Vascular Htn

Vascular Hypertension

Cholesterol Hypertension

Cholesterol Htn

Idiopathic Htn

Malignant Hypertension

Malignant Htn

Raised Blood Pressure

Cardiovascular Hypertension

Primary Htn - [Hypertension]

High Arterial Tension

High Blood Pressure Disorder

Ht - [Hypertension]

Htn - [Hypertension]

Hypertensive Vascular Disease

Hypertensive Vascular Degeneration

Coronary Heart Disease 1

Coronary Heart Disease

Coronary Heart Disease, Susceptibility To, 1

Chds1

Coronary Heart Disease, Susceptibility To

CHD

Heart, Coronary, Disease, Susceptibility To, Type 1

Coronary Arteriosclerosis

Coronary Artery Disease

Antiphospholipid Syndrome

Antiphospholipid Antibody Syndrome

Hughes Syndrome

Familial Antiphospholipid Syndrome

Aps

Lupus Anticoagulant, Familial

Anti-Phospholipid Syndrome

Apls

Classic Apls

Classic Antiphospholipid Syndrome

Acromegaloid Facial Appearance Syndrome

Anticardiolipin Syndrome

Placenta Accreta
Aortic Aneurysm, Familial Abdominal, 1

Abdominal Aortic Aneurysm

Aortic Aneurysm, Familial Abdominal 1

Aneurysm, Abdominal Aortic

AAA

Aortic Aneurysm, Abdominal

AAA1

Aortic Aneurysm, Familial Abdominal

Aortic Aneurysm Abdominal

Abdominal Aortic Aneurysms

Abdominal Aortic Aneurysm Without Mention Of Perforation Or Rupture

Abdomen Aneurysm

Abdominal Aorta Aneurysm

Aneurysm Of Abdominal Aorta

Aortic Abdomen Aneurysm

Aaa - [Abdominal Aortic Aneurysm]

Abdominal Aneurysm

Abdominal Aorta Aneurysm Rupture

Abdominal Aorta Aneurysm Ruptured

Abdominal Aortic Aneurysm Which Has Ruptured

Ruptured Aaa

Abdomen Aorta Aneurysm Ruptured

Abdomen Aorta Rupture

Abdomen Aortic Aneurysm Rupture

Abdomen Aneurysm Rupture

Abdomen Aortic Aneurysm Ruptured

Abdomen Aortic Rupture

Abdominal Aorta Rupture

Abdominal Aortic Rupture

Rupture Abdomen Aorta Aneurysm

Rupture Abdominal Aortic Aneurysm

Ruptured Abdomen Aneurysm

Ruptured Abdomen Aorta

Ruptured Abdomen Aortic

Ruptured Abdominal Aneurysm

Ruptured Abdominal Aorta

Ruptured Abdominal Aortic

Ruptured Aorta Abdominalis Aneurysm

False Abdomen Aorta Aneurysm Ruptured

False Abdominal Aortic Aneurysm Ruptured

False Abdominal Aorta Aneurysm Ruptured

False Abdomen Aortic Aneurysm Ruptured

Diabetes Mellitus

Diabetes

Chronic Venous Insufficiency
Respiratory Failure

Acute Respiratory Failure

Chronic Respiratory Failure

Respiratory Insufficiency

Acute-On-Chronic Respiratory Failure

Acute And Chronic Respiratory Failure

Respiratory Insufficiency/Failure

Chronic Respiratory Disease

Respiratory Disease

Pulmonary Valve Insufficiency

Chronic Disease Of Respiratory System

Respiration Disorders

Respiratory Tract Diseases

Lung Failure Nos

Pulmonary Failure

Arf - [Acute Respiratory Failure]

Acute Respiratory Insufficiency

Acute Pulmonary Insufficiency

Acute Respiration Failure

Chronic Respiration Failure

Sleep Apnea

Sleep Apnea Syndromes

Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy

Primary Dilated Cardiomyopathy

Idiopathic Dilated Cardiomyopathy

Congestive Cardiomyopathy

Idiopathic Dilation Cardiomyopathy

Primary Familial Dilated Cardiomyopathy

Cardiomyopathy, Dilated

DCM

Cardiomyopathy, Familial Dilated

Dilated Cardiomyopathy, Familial

Hypokinetic Dilated Cardiomyopathy, Familial

Familial Idiopathic Cardiomyopathy

Fdc

Cardiomyopathy, Familial Idiopathic

Idiopathic Cardiomegaly

Dilated Congestive Cardiomyopathy

Chronic Dilated Cardiomyopathy

Ccm - [Congestive Cardiomyopathy]

Cocm - [Congestive Cardiomyopathy]

Dcm - [Dilated Cardiomyopathy]

Dilated-Hypokinetic Cardiomyopathy

Congestive Idiopathic Cardiomyopathy

Primary Idiopathic Dilated Cardiomyopathy

Protein S Deficiency

Protein S Deficiency Disease

Hereditary Thrombophilia Due To Protein S Deficiency

Type 2 Diabetes Mellitus

Insulin Resistance

NIDDM

Diabetes Mellitus, Non-Insulin-Dependent

Type 2 Diabetes

T2D

Noninsulin-Dependent Diabetes Mellitus

Diabetes Mellitus, Type Ii

Maturity-Onset Diabetes

Insulin Resistance, Severe, Digenic

Diabetes Mellitus, Type 2

Diabetes Mellitus, Noninsulin-Dependent

Diabetes Mellitus, Noninsulin-Dependent, Association With

Diabetes Mellitus, Noninsulin-Dependent, Late Onset

Hypertension, Insulin Resistance-Related, Susceptibility To

Insulin Resistance, Susceptibility To

Non-Insulin-Dependent Diabetes Mellitus

Type Ii Diabetes Mellitus

Adult-Onset Diabetes Mellitus

Maturity-Onset Diabetes Mellitus

Diabetes Mellitus Type 2

Type Ii Diabetes

Type 2 Diabetes Mellitus, Susceptibility To

Diabetes, Type 2

Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To

Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To

Diabetes Mellitus, Type 2, Susceptibility To

Diabetes Mellitus, Noninsulin-Dependent, 2

Diabetes Mellitus, Type Ii, Susceptibility To

Hypertension, Insulin Resistance-Related

Adult-Onset Diabetes

Aodm

Diabetes Mellitus, Adult-Onset

Diabetes Mellitus Type Ii

Diabetes Mellitus Type 2, Susceptibility To

Diabetes, Type Ii, Susceptibility To

Diabetes Type 2

Diabetes Mellitus

Adult Onset Diabetes

Maturity Onset Diabetes

Nonketotic Diabetes

Non-Insulin Dependent Diabetes Mellitus

T2dm - [Type 2 Diabetes Mellitus]

Niddm - [Non Insulin Dependent Diabetes Mellitus]

Dm2

Dm Type Ii

Diabetic Type 2

Insulin Requiring Type 2 Diabetes

Noninsulin Dependent Diabetes

Non-Insulin-Dependent Diabetes Mellitus Without Complications

Diabetes Due To Insulin Secretory Defect

Diabetes Mellitus Due To Insulin Secretory Defect

Non-Insulin-Dependent Diabetes Of The Young

Senile Diabetes

Nonketotic Hyperglycaemia

Stable Diabetes

Alpha-1-Antitrypsin Deficiency

Alpha 1-Antitrypsin Deficiency

Alpha-1 Antitrypsin Deficiency

Aat Deficiency

Aatd

A1ATD

Emphysema Due To Aat Deficiency

A1at Deficiency

Hemorrhagic Diathesis Due To Antithrombin Pittsburgh

Emphysema-Cirrhosis, Due To Aat Deficiency

Alpha-1 Antiprotease Deficiency

Alpha 1 Antitrypsin Deficiency

Aat

Alpha-1 Protease Inhibitor Deficiency

Alpha-1 Related Emphysema

Genetic Emphysema

Hereditary Pulmonary Emphysema

Inherited Emphysema

Alpha-1-Proteinase Inhibitor Deficiency

Alpha1-Antitrypsin Deficiency

Alpha-1-Antitrypsin Deficiency, Autosomal Recessive

Emphysema, Hereditary Pulmonary

Aatd - [Alpha-1-Antitrypsin] Deficiency

Portal Vein Thrombosis

Phlebitis Of Portal Vein

Deep Vein Thrombosis Of Portal Vein

Portal Thrombosis

Pvt - [Portal Vein Thrombosis]

Portal Venous Thrombosis

Portal Venous Embolism

Portal Venous Obstruction

Portal Venous Block

Portal Vein Embolism

Portal Vein Block

Portal Obstruction

Portal Embolism

Portal Block

Hepatic Portal Vein Obstruction

Occlusion Of Hepatic Portal Vein

Portal Vein Obstruction

Amaurosis Fugax

Transient Monocular Blindness

Momentary Blindness

Af - [Amaurosis Fugax]

Transient Vision Loss, Spontaneous

Amaurosis Fugax, Course Of Resolution Unspecified

Subendocardial Myocardial Infarction
Urinary Tract Obstruction

Obstructive Uropathy

Urinary Obstruction

Urologic Diseases

Prediabetes Syndrome

Impaired Glucose Tolerance

Prediabetes

Prediabetic State

IGT

Igt - [Impaired Glucose Tolerance]

Impaired Glucose Tolerance With Unspecified Complication

Impaired Glucose Tolerance Without Complication

Abnormal Glucose Tolerance

Plasminogen Activator Inhibitor-1 Deficiency

Hyperfibrinolysis Due To Pai1 Deficiency

Plasminogen Activator Inhibitor Type 1 Deficiency

Pai-1 Deficiency

Pai1 Deficiency

Plasminogen Activator Inhibitor 1 Deficiency

PAI-1D

Plasminogen Activator Inhibitor, Type I

Deficiency, Plasminogen Activator Inhibitor-1

Thrombophlebitis

Phlebitis And Thrombophlebitis Of Superficial Vessels Of Lower Extremities

Superficial Thrombophlebitis Of Leg

Thrombophlebitis Of A Superficial Leg Vein

Thrombophlebitis Of Superficial Veins Of Lower Extremity

Vascular Disease

Vascular Diseases

Aneurysm

Spinal Cord Ischemia

Spinal Cord Vascular Diseases

Vascular Tissue Disease

Vascular Anomaly

Abdominal Obesity-Metabolic Syndrome 1

Metabolic Syndrome X

Metabolic Syndrome

AOMS1

Dysmetabolic Syndrome X

Metabolic Disease

Abdominal Obesity Metabolic Syndrome

Afibrinogenemia, Congenital

Congenital Afibrinogenemia

Afibrinogenemia

Factor I Deficiency

Familial Afibrinogenemia

Hypofibrinogenemia, Congenital

Fibrinogen Deficiency

Afibrinogenemia Congenital

CAFBN

Congenital Hypofibrinogenemia

Hypofibrinogenemia

Complement Factor I Deficiency

Non-Alcoholic Fatty Liver Disease

Fatty Liver

Non-Alcoholic Fatty Liver

Nafld

Nonalcoholic Fatty Liver Disease

Nonalcoholic Steatohepatitis

Steatosis

Nafl

Nash

Non-Alcoholic Steatohepatitis

Susceptibility To Nonalcoholic Fatty Liver Disease

Steatohepatitis

Fatty Degeneration

Non-Alcoholic Fatty Liver Disease Without Mention Of Non-Alcoholic Steatohepatitis

Nafld Without Nash

Nafld Without Mention Of Nash

Pulmonary Artery Disease

Abnormality Of The Pulmonary Artery

Arthrogryposis, Distal, Type 2b2

DA2B2

Distal Arthrogryposis Type 2b2

Arthrogryposis, Distal, 2b2

Atherosclerosis Susceptibility

Atherosclerosis

Atherosclerosis, Susceptibility To

ATHS

Atherogenic Lipoprotein Phenotype

Alp

Arteriosclerosis

Familial Hyperlipidemia

Familial Hyperlipoproteinemia

Hyperlipidaemia

Hyperlipoproteinemias

Hyperlipemia

Hyperlipidemias

Hyperlipidemia

Vein Disease

Disorder Of Vein

Hyperglycemia
Peripheral Vascular Disease

Peripheral Arterial Disease

Arterial Occlusive Disease

Arterial Occlusive Diseases

Pad

Peripheral Vascular Diseases

Peripheral Occlusive Disease

Peripheral Arterial Diseases

Helicobacter Infections

Hepatic Veno-Occlusive Disease

Veno-Occlusive Disease

Sinusoidal Obstruction Syndrome

Hepatic Venoocclusive Disease

Venoocclusive Disease

Hepatic Vein Thrombosis

Budd-Chiari Syndrome

Hepatic Vein Occlusion

Veno-Occlusive Disease Of The Liver

Endocarditis
Cerebral Palsy

Infantile Cerebral Palsy

Mixed Cerebral Palsy

Palsy Cerebral

Palsy, Cerebral

Cerebral Palsy, Mixed

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Arthrogryposis, Distal, Type 2b1

Sheldon-Hall Syndrome

Freeman-Sheldon Syndrome Variant

Distal Arthrogryposis Type 2b1

DA2B1

Arthrogryposis Multiplex Congenita, Distal, Type 2b

Shs

Distal Arthrogryposis Type 2b

Fssv

Arthrogryposis Multiplex Congenita Distal Type 2b

Arthrogryposis Multiplex Congenita Distal Type Ii With Craniofacial Abnormalities

Da2b

Arthrogryposis Multiplex Congenita, Distal, Type Ii, With Craniofacial Abnormalities

Distal Arthrogryposis Type Iib

Freeman Sheldon Syndrome, Variant

Freeman Sheldon Variant

Arthrogryposis, Distal, 2b1

Amcd2b

Interstitial Lung Disease 2

Idiopathic Pulmonary Fibrosis

Ipf

Fibrocystic Pulmonary Dysplasia

Pulmonary Fibrosis, Idiopathic

Pulmonary Fibrosis, Idiopathic, Susceptibility To

ILD2

Idiopathic Pulmonary Fibrosis, Familial

Fibrosing Alveolitis, Cryptogenic

Uip

Cryptogenic Fibrosing Alveolitis

Fibrosing Alveolitis

Interstitial Pneumonitis, Usual

Familial Idiopathic Pulmonary Fibrosis

Idiopathic Fibrosing Alveolitis, Chronic Form

Usual Interstitial Pneumonia

Fibrosing Alveolitis Cryptogenic

Hamman-Rich Disease

Idiopathic Pulmonary Fibrosis Familial

Interstitial Pneumonitis Usual

Fibrosis Idiopathic Pulmonary

Fibrosis, Pulmonary, Idiopathic

Hamman-Rich Syndrome

Chronic Idiopathic Pulmonary Fibrosis

Acute Interstitial Pneumonia

Interstitial Pulmonary Fibrosis

Ipf - [Idiopathic Pulmonary Fibrosis]

Idiopathic Lung Fibrosis

Fibrosing Lung Disease

Pulmonary Fibrosis Nos

Fibrosing Pneumonitis

Acute Myocardial Infarction

Cardiac Attack

Heart Attack

Hemorrhagic Disease

Hemorrhagic Disorders

Hemorrhagic Diathesis

Hemorrhagic Diseases

Bleeding Tendency

Acquired Coagulation Factor Inhibitor Disorder

Acquired Inhibitor Of Coagulation

Antithrombinaemia

Antithromboplastinogenaemia

Circulating Anticoagulant Disorder

Haemorrhagic Disorder Due To Antithrombinaemia

Haemorrhagic Disorder Due To Excess Administered Heparin

Antithromboplastinaemia

Haemorrhagic Disorder Due To Hyperheparinemia

Abdominal Obesity-Metabolic Syndrome Quantitative Trait Locus 2

Abdominal Obesity-Metabolic Syndrome

Abdominal Obesity Metabolic Syndrome

Metabolic Syndrome X

Aoms2

Aoms1

Pseudoxanthoma Elasticum

PXE

Gronblad-Strandberg Syndrome

Pseudoxanthoma Elasticum, Modifier Of Severity Of

Gronblad-Strandberg-Touraine Syndrome

Gronblad Strandberg Syndrome

Groenblad-Strandberg Syndrome

Nevus Elasticus

Pxe - [Pseudoxanthoma Elasticum]

Aortic Aneurysm, Familial Thoracic 1

Thoracic Aortic Aneurysm

Annuloaortic Ectasia

Familial Thoracic Aortic Aneurysm And Aortic Dissection

Familial Aortic Dissection

Familial Taad

Congenital Aneurysm Of Ascending Aorta

Familial Aortic Aneurysm

Familial Thoracic Aortic Aneurysm

Familial Thoracic Aortic Aneurysm And Dissection

Aortic Aneurysm, Thoracic

AAT1

Faa1

Aortic Dissection, Familial

Aortic Aneurysm, Familial Thoracic

Aneurysm, Thoracic Aortic

Faa

Ftaad

Taa

Taad

Cystic Medial Necrosis Of Aorta

Familial Non-Syndromic Thoracic Aortic Aneurysm And Aortic Dissection

Aortic Aneurysm Thoracic

Familial Aortic Aneurysms

Aneurysm, Aortic, Thoracic, Familial, Type 1

Aneurysm Of Thoracic Aorta

Intrathoracic Aneurysm

Thoracic Aorta Aneurysm

Thoracic Aortic Aneurysm Without Rupture

Thoracic Aneurysm

Thorax Arterial Aneurysm

Thoracic Artery Aneurysm

Thoracic Arterial Aneurysm

Thorax Aneurysm

Thorax Aortic Aneurysm

Dissection Of Thoracic Aorta

Hepatic Vascular Disease

Vascular Disorder Of Liver

Placental Insufficiency

Uteroplacental Vascular Insufficiency

Retinal Artery Occlusion

Retina Artery Narrowing

Retinal Artery Spasm

Spasm Of Ophthalmic Artery

Retinal Spasm

Vasospasm Of Retina

Severe Pre-Eclampsia

Severe Preeclampsia

Antepartum Severe Pre-Eclampsia

Postpartum Severe Pre-Eclampsia

Severe Pre-Eclampsia, With Delivery

Severe Toxemia

Severe Pre-Eclampsia, Antepartum Condition Or Complication

Severe Pre-Eclampsia, Postpartum Condition Or Complication

Severe Puerperal Pre-Eclampsia

Severe Pre-Eclamptic Toxaemia

Severe Pet - [Pre-Eclamptic Toxaemia]

Autism Spectrum Disorder

Asd

Autism Spectrum Disorders

Autistic Continuum

Pervasive Developmental Disorder

Pervasive Development Disorder

Autistic Behavior

Autistic Disorder

Autistic

Autistic Disorder Of Childhood Onset

Infantile Autism

Childhood Autism

Kanner Syndrome

Pervasive Developmental Delay Nos

Pervasive Developmental Disorder, Not Otherwise Specified

Polycystic Ovary Syndrome

Polycystic Ovarian Syndrome

Pcos

Polycystic Ovaries

Stein-Leventhal Syndrome

Multicystic Ovaries

Polycystic Ovarian Disease

Polycystic Ovary

Sclerocystic Ovaries

Sclerocystic Ovary Syndrome

Stein-Leventhal Synd.

Cystic Disease Of Ovaries

Cystic Disease Of Ovary

Pco

Pcod

Sclerocystic Ovarian Degeneration

Polycystic Ovary Syndrome, Susceptibility To

Pcos - [Polycystic Ovary Syndrome]

Polycystic Ovary Nos

Pco - [Polycystic Ovary]

Thrombophilia Due To Thrombin Defect

Venous Thromboembolism

Venous Thrombosis

Thrombophilia Due To Factor 2 Defect

Thromboembolism

THPH1

Thromboembolism, Susceptibility To

Venous Thromboembolism, Susceptibility To

Venous Thrombosis, Protection Against

Prothrombin-Related Thrombophilia

Hyperprothrombinemia

Venous Thrombosis, Susceptibility To

Thrombophilia 1 Due To Thrombin Defect

F2-Related Thrombophilia

Factor Ii-Related Thrombophilia

Prothrombin 20210g>A Thrombophilia

Prothrombin G20210a Thrombophilia

Prothrombin Thrombophilia

Thrombotic Thrombocytopenic Purpura

Purpura, Thrombotic Thrombocytopenic

Ttp

Thrombotic Thrombocytopenic Purpura, Acquired

Idiopathic Thrombotic Thrombocytopenic Purpura

Moschcowitz Disease

Moschcowitz'S Syndrome

Moschowitz Syndrome

Chronic Relapsing Thrombotic Thrombocytopenic Purpura

Familial Thrombotic Thrombocytopenia Purpura

Moschkowitz Disease

Purpura Thrombotic Thrombocytopenic

Familial Thrombotic Thrombocytopenic Purpura

Microangiopathic Hemolytic Anemia

Congenital Thrombotic Thrombocytopenic Purpura

Autoimmune Thrombotic Thrombocytopenic Purpura

Ttp - [Thrombotic Thrombocytopenic Purpura]

Moschcowitz Syndrome

Pulmonary Fibrosis

Fibrosis Of Lung

Advanced Sleep Phase Syndrome, Familial, 1

Advanced Sleep Phase Syndrome 1

FASPS1

Familial Advanced Sleep Phase Syndrome 1

Sleep Phase Syndrome, Advanced, Familial, Type 1

Overnutrition
Heart Disease

Heart Failure

Congenital Heart Disease

Heart Diseases

Congenital Heart Defects

Congenital Heart Defect

Congenital Anomaly Of Heart

Heart Defect

Heart Malformation

Heart-Congenital Defect

Congenital Heart Disorder

Heart Defects Congenital

Heart Defects, Congenital

Heart Defects

Heart Disease, Congenital

Disease, Heart, Congenital

Congestive Heart Failure

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SERPINE1 RGD RGD:3249
Bos taurus SERPINE1 VGNC VGNC:34476
Macaca mulatta SERPINE1 VGNC VGNC:77362
Felis catus SERPINE1 VGNC VGNC:68688
Mus musculus SERPINE1 MGD MGI:97608
Canis familiaris SERPINE1 VGNC VGNC:46036
Others SERPINE1 NCBI