HSD17B11 - hydroxysteroid 17-beta dehydrogenase 11 Gene

Homo sapiens

Also known as DHRS8; PAN1B; RETSDR2; SDR16C2; 17BHSD11; 17-BETA-HSD11; 17-BETA-HSDXI

Gene ID: 51170 | Gene type: protein coding

About HSD17B11

Cytogenetic location: 4q22.1 Genomic coordinates (GRCh38): 4:87,336,515-87,391,188 (from NCBI)

This gene has 7 transcripts (splice variants), 122 orthologues and 25 paralogues. Broad expression in small intestine (RPKM 142.3), duodenum (RPKM 102.8) and 22 other tissues.

Summary

Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009]

HSD17B11 Products(1)

mRNA	Protein	Name
NM_016245.5	NP_057329.3	estradiol 17-beta-dehydrogenase 11 precursor

HSD17B11 Protein Structure

adh_short

0
100
200
300 a.a.

Protein Preferred Names

Protein Names

estradiol 17-beta-dehydrogenase 11

17-beta-hydroxysteroid dehydrogenase type XI

Related Diseases

Diseases

Alias

Lymphoma

Lymphoid Cancer	Lymphomas
Lymphoid Cancers	Lymphoid Neoplasm
Lymphoma Nos	Nhl - [Non-Hodgkin Lymphoma]
Non-Hodgkin Lymphoma	Non-Hodgkin Lymphoma, Nos
Non-Hodgkin Malignant Lymphoma Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06391	HSD17B11 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	HSD17B11	MGD	MGI:2149821
Rattus norvegicus	HSD17B11	RGD	RGD:1303235
Bos taurus	HSD17B11	VGNC	VGNC:29970
Macaca mulatta	HSD17B11	VGNC	VGNC:73431
Felis catus	HSD17B11	VGNC	VGNC:62846

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