2. Gene
  3. Icosl - icos ligand Gene

Icosl - icos ligand Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as B7h; GI50; GL50; B7-H2; LICOS; B7RP-1; GL50-B; ICOS-L; Icoslg; Ly115l; mKIAA0653

Gene ID: 50723 | Gene type: protein coding

About Icosl

Summary

Predicted to enable identical protein binding activity and signaling receptor binding activity. Involved in positive regulation of interleukin-4 production. Located in external side of plasma membrane. Is integral component of plasma membrane. Is expressed in several structures, including extraembryonic component; gonad; hemolymphoid system gland; liver; and stomach. Orthologous to human ICOSLG (inducible T cell costimulator ligand). [provided by Alliance of Genome Resources, Apr 2022]

Icosl Products(1)

mRNA Protein Name
NM_015790.3 NP_056605.1 ICOS ligand precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10657606 MGI
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of interleukin-4 production IMP
IMP: Inferred from mutant phenotype
11343123 MGI
Cellular Component GO Annotation Evidence Reference Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
10657606 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10657606 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ICOS ligand

B7 homolog 2

B7-like protein Gl50

B7-related protein 1

Recombinant Icosl Proteins

Cat. No. Product Name Accession Purity
HY-P73119 B7-H2/ICOSLG Protein, Mouse (HEK293, His-Fc) Q9JHJ8-1 (E47-K279) ≥95%
HY-P73120 B7-H2/ICOSLG Protein, Mouse (HEK293, His) Q9JHJ8-1 (E47-K279) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-162810 ICOS-IN-1 / Unkown

Orthologs Information

Species Symbol Source ID
Macaca fascicularis Icosl NCBI
Rattus norvegicus Icosl NCBI