2. Gene
  3. TXNDC11 - thioredoxin domain containing 11 Gene

TXNDC11 - thioredoxin domain containing 11 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as EFP1

Gene ID: 51061 | Gene type: protein coding

About TXNDC11

Cytogenetic location: 16p13.13 Genomic coordinates (GRCh38): 16:11,679,083-11,742,857 (from NCBI)

This gene has 9 transcripts (splice variants), 215 orthologues and 13 paralogues. Ubiquitous expression in fat (RPKM 51.7), thyroid (RPKM 30.4) and 25 other tissues.

Summary

Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TXNDC11 Products(5)

mRNA Protein Name
NM_001303447.2 NP_001290376.1 thioredoxin domain-containing protein 11 isoform 1
NM_001324022.2 NP_001310951.1 thioredoxin domain-containing protein 11 isoform 3
NM_001324024.2 NP_001310953.1 thioredoxin domain-containing protein 11 isoform 4
NM_001324025.2 NP_001310954.1 thioredoxin domain-containing protein 11 isoform 4
NM_015914.7 NP_056998.4 thioredoxin domain-containing protein 11 isoform 2

TXNDC11 Protein Structure

Thioredoxin

Thioredoxin: Thioredoxin (116 - 210)

Thioredoxin

Thioredoxin: Thioredoxin (693 - 774)

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  • 985 a.a.
Protein Preferred Names Protein Names

thioredoxin domain-containing protein 11

EF-hand binding protein 1

TXNDC11 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
TXNDC11 Q6PKC3 PRPF18 Homo sapiens Q99633
Validated Y2H
32296183
Intra
TXNDC11 Q6PKC3 HTT Homo sapiens P42858
Y2H
17500595
Intra
TXNDC11 Q6PKC3 RAB2B Homo sapiens Q8WUD1
Validated Y2H
32296183
Intra
TXNDC11 Q6PKC3 ZNF417 Homo sapiens Q8TAU3
Validated Y2H
32296183
Cross
TXNDC11 Q6PKC3 Q9WMX2-PRO_0000037551 Hepatitis C virus Q9WMX2-PRO_0000037551
Y2H Prey Pooling
18985028
Cross
TXNDC11 Q6PKC3 Q9WMX2-PRO_0000037551 Hepatitis C virus Q9WMX2-PRO_0000037551
Pull Down
18985028
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15289 TXNDC11 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TXNDC11 VGNC VGNC:79678
Mus musculus TXNDC11 MGD MGI:1923620
Bos taurus TXNDC11 VGNC VGNC:36534
Felis catus TXNDC11 VGNC VGNC:66724
Rattus norvegicus TXNDC11 RGD RGD:1307538
Canis familiaris TXNDC11 VGNC VGNC:48010