MRTO4 - MRT4 homolog, ribosome maturation factor Gene

Homo sapiens

Also known as MRT4; C1orf33; dJ657E11.4

Gene ID: 51154 | Gene type: protein coding

About MRTO4

This gene has 3 transcripts (splice variants) and 227 orthologues. Ubiquitous expression in appendix (RPKM 7.6), lymph node (RPKM 7.5) and 25 other tissues.

Summary

This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly. [provided by RefSeq, Jul 2008]

MRTO4 Products(1)

mRNA	Protein	Name
NM_016183.4	NP_057267.2	mRNA turnover protein 4 homolog

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21044950	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MRTO4 Protein Structure

Ribosomal_L10

0
100
200
239 a.a.

Protein Preferred Names

Protein Names

mRNA turnover protein 4 homolog

60S acidic ribosomal protein PO

Recombinant MRTO4 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75465	C1orf33/MRTO4 Protein, Human (His)	Q9UKD2 (M1-D239)	≥95%

Related Diseases

Diseases

Alias

Branchiootorenal Syndrome 1

Melnick-Fraser Syndrome	BOR1
Branchiootorenal Dysplasia	Branchiootorenal Syndrome 1, With Or Without Cataracts
Bor Syndrome 1	Branchiootorenal Dysplasia 1
Branchio-Oto-Renal Dysplasia 1	Branchio-Oto-Renal Syndrome Type 1
Branchiootorenal Syndrome, With/Without Cataract, Type 1	Branchio-Oto-Renal Syndrome

Shwachman-Diamond Syndrome 1

Shwachman-Diamond Syndrome	Shwachman Syndrome
Shwachman-Bodian-Diamond Syndrome	Sds
Pancreatic Insufficiency And Bone Marrow Dysfunction	Shwachman-Bodian Syndrome
SDS1	Lipomatosis Of Pancreas, Congenital
Congenital Lipomatosis Of Pancreas	Shwachman-Diamond Type Metaphyseal Dysplasia
Metaphyseal Chondrodysplasia, Shwachman Type	Shwachman-Diamond-Oski Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08695	MRTO4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MRTO4	MGD	MGI:1917152
Bos taurus	MRTO4	VGNC	VGNC:31680
Felis catus	MRTO4	VGNC	VGNC:63629
Canis familiaris	MRTO4	VGNC	VGNC:84430
Rattus norvegicus	MRTO4	RGD	RGD:1311709
Others	MRTO4	NCBI

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