2. Gene
  3. GPN3 - GPN-loop GTPase 3 Gene

GPN3 - GPN-loop GTPase 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ATPBD1C

Gene ID: 51184 | Gene type: protein coding

About GPN3

This gene has 10 transcripts (splice variants), 213 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 19.7), fat (RPKM 10.4) and 25 other tissues.

Summary

Predicted to enable GTPase activity. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

GPN3 Products(3)

mRNA Protein Name
NM_001164372.2 NP_001157844.1 GPN-loop GTPase 3 isoform 2
NM_001164373.2 NP_001157845.1 GPN-loop GTPase 3 isoform 3
NM_016301.4 NP_057385.3 GPN-loop GTPase 3 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25241168 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPN3 Protein Structure

ATP_bind_1

ATP_bind_1: Conserved hypothetical ATP binding protein (8 - 254)

  • 0
  • 100
  • 200
  • 284 a.a.
Protein Preferred Names Protein Names

GPN-loop GTPase 3

ATP-binding domain 1 family member C

Related Diseases

Diseases Alias
B-Lymphoblastic Leukemia/Lymphoma With Tcf3-Pbx1

B Acute Lymphoblastic Leukemia With T(1

19)(Q23

P13.3)

E2a-Pbx1 (Tcf3-Pbx1)

B-All With Tcf3-Pbx1

B-Lymphoblastic Leukemia/Lymphoma With T(1

19)(Q23

P13.3)

Tcf3-Pbx1
Microcephaly, Autosomal Dominant

Autosomal Dominant Microcephaly

Microcephaly Autosomal Dominant

Autosomal Dominant Primary Microcephaly

Microcephaly With Autosomal Dominant Inheritance
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05647 GPN3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GPN3 VGNC VGNC:41388
Mus musculus GPN3 MGD MGI:1289326
Bos taurus GPN3 VGNC VGNC:29540
Rattus norvegicus GPN3 RGD RGD:1303034
Felis catus GPN3 VGNC VGNC:107707
Macaca mulatta GPN3 VGNC VGNC:73040