THEG - theg spermatid protein Gene

Homo sapiens

Also known as CT56; THEG1

Gene ID: 51298 | Gene type: protein coding

About THEG

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:361,747-376,026 (from NCBI)

This gene has 4 transcripts (splice variants), 106 orthologues and 1 paralogue. Restricted expression toward testis (RPKM 7.1).

Summary

This gene is specifically expressed in the nucleus of haploid male germ cells. The orthologous gene in mice encodes a protein that may play a role in protein assembly through interactions with T-complex protein 1 subunit epsilon. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

THEG Products(2)

mRNA	Protein	Name
NM_016585.5	NP_057669.1	testicular haploid expressed gene protein isoform 1
NM_199202.3	NP_954672.1	testicular haploid expressed gene protein isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

THEG Protein Structure

THEG

0
100
200
300
379 a.a.

Protein Preferred Names

Protein Names

testicular haploid expressed gene protein

Theg homolog

THEG Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SPMAP2	Q9P2T0	LAMP2	Homo sapiens	P13473-2	Validated Y2H	32814053
Intra	SPMAP2	Q9P2T0	LAMP2	Homo sapiens	P13473-2	Y2H Pooling	32814053
Intra	SPMAP2	Q9P2T0	LAMP2	Homo sapiens	P13473-2	Y2H Array	32814053
Intra	SPMAP2	Q9P2T0	GSN	Homo sapiens	P06396	Validated Y2H	32814053
Intra	SPMAP2	Q9P2T0	GSN	Homo sapiens	P06396	Y2H Pooling	32814053
Intra	SPMAP2	Q9P2T0	GSN	Homo sapiens	P06396	Y2H Array	32814053
Intra	SPMAP2	Q9P2T0	HIP1	Homo sapiens	O00291	Y2H Pooling	32814053
Intra	SPMAP2	Q9P2T0	HIP1	Homo sapiens	O00291	Validated Y2H	32814053
Intra	SPMAP2	Q9P2T0	HIP1	Homo sapiens	O00291	Y2H Array	32814053
Intra	SPMAP2	Q9P2T0	FHL3	Homo sapiens	Q13643	Y2H Array	32296183
Intra	SPMAP2	Q9P2T0	FHL3	Homo sapiens	Q13643	Y2H Prey Pooling	32296183
Intra	SPMAP2	Q9P2T0	DR1	Homo sapiens	Q01658	Y2H Pooling	32814053
Intra	SPMAP2	Q9P2T0	DR1	Homo sapiens	Q01658	Validated Y2H	32814053
Intra	SPMAP2	Q9P2T0	DR1	Homo sapiens	Q01658	Y2H Array	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14483	THEG Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	THEG	MGD	MGI:1338756
Rattus norvegicus	THEG	RGD	RGD:1309240
Macaca mulatta	THEG	VGNC	VGNC:78379
Felis catus	THEG	VGNC	VGNC:66158
Bos taurus	THEG	VGNC	VGNC:35832
Canis familiaris	THEG	VGNC	VGNC:47339

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