2. Gene
  3. MEX3C - mex-3 RNA binding family member C Gene

MEX3C - mex-3 RNA binding family member C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as RKHD2; BM-013; MEX-3C; RNF194

Gene ID: 51320 | Gene type: protein coding

About MEX3C

Cytogenetic location: 18q21.2 Genomic coordinates (GRCh38): 18:51,174,550-51,197,681 (from NCBI)

This gene has 3 transcripts (splice variants), 144 orthologues and 3 paralogues. Broad expression in testis (RPKM 32.6), lymph node (RPKM 11.1) and 24 other tissues.

Summary

This gene encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. The protein interacts with mRNA via the KH domains, and the protein shuttles between the nucleus and cytoplasm. Polymorphisms in this gene may contribute to hypertension. [provided by RefSeq, Oct 2009]

MEX3C Products(1)

mRNA Protein Name
NM_016626.5 NP_057710.3 RNA-binding E3 ubiquitin-protein ligase MEX3C
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables RNA binding IDA
IDA: Inferred from direct assay
23408853 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
22863774 GOA
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
22863774 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MEX3C Protein Structure

KH_1

KH_1: KH domain (234 - 293)

KH_1

KH_1: KH domain (328 - 387)

zf-C3HC4_3

zf-C3HC4_3: Zinc finger, C3HC4 type (RING finger) (605 - 653)

  • 0
  • 200
  • 400
  • 600
  • 659 a.a.
Protein Preferred Names Protein Names

RNA-binding E3 ubiquitin-protein ligase MEX3C

RING finger and KH domain-containing protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08374 MEX3C Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MEX3C RGD RGD:1309023
Canis familiaris MEX3C VGNC VGNC:43185
Felis catus MEX3C VGNC VGNC:63469
Bos taurus MEX3C VGNC VGNC:31420
Mus musculus MEX3C MGD MGI:2652843
Macaca mulatta MEX3C VGNC VGNC:74597