Ywhab - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Gene

Mus musculus

Also known as 14-3-3b; 1300003C17Rik

Gene ID: 54401 | Gene type: protein coding

About Ywhab

Summary

Enables protein domain specific binding activity. Acts upstream of or within protein targeting. Predicted to be located in cytosol; nucleus; and perinuclear region of cytoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in cytoplasm. Is expressed in several structures, including genitourinary system; nervous system; palatal shelf; retina layer; and thymus. Orthologous to human YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta). [provided by Alliance of Genome Resources, Apr 2022]

Ywhab Products(1)

mRNA	Protein	Name
NM_018753.6	NP_061223.2	14-3-3 protein beta/alpha

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	12937170	MGI
enables protein domain specific binding	IDA IDA: Inferred from direct assay	12446771	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within protein targeting	IDA IDA: Inferred from direct assay	12446771	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

14-3-3 protein beta/alpha

14-3-3 protein beta	KCIP-1
protein kinase C inhibitor protein 1	tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide

Ywhab Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Ywhab	Q9CQV8	Prkce	Mus musculus	P16054	Pull Down	18237277
Intra	Ywhab	Q9CQV8	Prkce	Mus musculus	P16054	Pull Down	18604201
Intra	Ywhab	Q9CQV8	Synpo2	Mus musculus	Q91YE8	CoIP	15883195

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Ywhab Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71850	KCIP-1 Protein, Mouse (P.pastoris, His)	Q9CQV8-1 (M1-N246)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15940	YWHAB Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ywhab	NCBI	NCBI:7529
Macaca fascicularis	Ywhab	NCBI	NCBI:101926442

Name
Email *

	Sorry, but the email address you supplied was invalid.