1. Gene
  2. YWHAB - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta Gene

YWHAB - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta Gene

Homo sapiens

Also known as HS1; GW128; YWHAA; KCIP-1; HEL-S-1

Gene ID: 7529 | Gene type: protein coding

About YWHAB

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:44,885,705-44,908,532 (from NCBI)

This gene has 8 transcripts (splice variants), 269 orthologues and 6 paralogues. Ubiquitous expression in brain (RPKM 158.2), lymph node (RPKM 85.8) and 24 other tissues.

Summary

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both Plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

YWHAB Products(2)

mRNA Protein Name
NM_003404.5 NP_003395.1 2014/3/3 protein beta/alpha
NM_139323.4 NP_647539.1 2014/3/3 protein beta/alpha

YWHAB Protein Structure

14-3-3

14-3-3: 14-3-3 protein (6 - 237)

  • 0
  • 100
  • 200
  • 246 a.a.
Protein Preferred Names Protein Names

14-3-3 protein beta/alpha

14-3-3 alpha

Recombinant YWHAB Proteins

Cat. No. Product Name Accession Purity
HY-P74439 14-3-3 beta Protein, Human (GST) P31946 (M1-N246) ≥95%
HY-P74440 14-3-3 beta Protein, Human P31946 (M1-N246) ≥95%
HY-P700304 14-3-3 beta Protein, Human (His) P31946 (M1-N246) ≥95%

Related Diseases

Diseases Alias
Chlamydia

Chlamydial Infection

Chlamydia Trachomatis Infectious Disease

Chlamydial Disease

Chlamydia Infections

Eosinophilic Meningitis

Eosinophilic Meningoencephalitis Due To Angiostrongylus Cantonensis

Hyperinsulinemic Hypoglycemia, Familial, 5

Hyperinsulinism Due To Insr Deficiency

HHF5

Familial Hyperinsulinemic Hypoglycemia 5

Hyperinsulinemic Hypoglycemia Due To Insr Deficiency

Hyperinsulinemic Hypoglycemia Due To Insulin Receptor Deficiency

Congenital Hyperinsulinism

Persistent Hyperinsulinemic Hypoglycemia Of Infancy

Phhi

Hyperinsulinemic Hypoglycemia Familial 5

Chronic Meningitis
Lymphogranuloma Venereum

Climatic Or Tropical Bubo

Durand-Nicolas-Favre Disease

Lymphogranuloma Inguinale

Poradenitis Inguinale

Strumous Bubo

Lgv

Granuloma Inguinale

Donovanosis

Pudendal Ulcer

Granuloma Inguinale Tropicum

Granuloma Pudendi Tropicum

Chromosome 17p13.3, Centromeric, Duplication Syndrome

Chromosome 17p13.3 Duplication Syndrome

17p13.3 Duplication Syndrome

17p13.3 Microduplication Syndrome

Trisomy 17p13.3

Chromosome 17p13.3 Centromeric Duplication Syndrome

Dup(17)(P13.3)

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris YWHAB VGNC VGNC:48508
Rattus norvegicus YWHAB RGD RGD:61998
Mus musculus YWHAB MGD MGI:1891917
Felis catus YWHAB VGNC VGNC:67154
Macaca mulatta YWHAB VGNC VGNC:78819
Bos taurus YWHAB VGNC VGNC:37044
Macaca fascicularis YWHAB NCBI NCBI:101926442
Others YWHAB NCBI