MXRA8 - matrix remodeling associated 8 Gene

Homo sapiens

Also known as ASP3

Gene ID: 54587 | Gene type: protein coding

About MXRA8

Cytogenetic location: 1p36.33 Genomic coordinates (GRCh38): 1:1,352,689-1,363,541 (from NCBI)

This gene has 10 transcripts (splice variants), 249 orthologues and 14 paralogues. Broad expression in gall bladder (RPKM 26.7), fat (RPKM 25.8) and 22 other tissues.

Summary

Predicted to be involved in establishment of glial blood-brain barrier. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

MXRA8 Products(5)

mRNA	Protein	Name
NM_001282582.2	NP_001269511.1	matrix remodeling-associated protein 8 isoform 2 precursor
NM_001282583.2	NP_001269512.1	matrix remodeling-associated protein 8 isoform 4
NM_001282584.2	NP_001269513.1	matrix remodeling-associated protein 8 isoform 3 precursor
NM_001282585.1	NP_001269514.1	matrix remodeling-associated protein 8 isoform 1 precursor
NM_032348.4	NP_115724.1	matrix remodeling-associated protein 8 isoform 2 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MXRA8 Protein Structure

V-set

0
100
200
300
400
442 a.a.

Protein Preferred Names

Protein Names

matrix remodeling-associated protein 8

limitrin

Recombinant MXRA8 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P700876	MXRA8 Protein, Human (HEK293, His)	Q9BRK3-1 (V20-Q341)	≥95%

Related Diseases

Diseases

Alias

Chikungunya

Chikungunya Fever	Arbovirus A Chikungunya Type
Chik	Chikv Infection
Ck	Chikungunya Virus Infection
Chikungunya Haemorrhagic Fever	Chikungunya Viral Disease
Chikungunya Mosquito-Borne Viral Fever

Ross River Fever

Ross River Virus Disease

Ross River Virus Infection

Necatoriasis

Miner'S Anaemia	Negro Cachexia
Dochmiasis	Ground Itch Disease
Brickmaker'S Chlorosis	Coolie Itch Anaemia
Cachexia Aquosa	Dew Itch Anaemia
Brickmaker'S Anaemia	Tunnel Worker'S Anaemia
Egyptian Anaemia	Tunnel Worker'S Disease
Miner'S Cachexia	Greisinger Disease
Tropical Chlorosis	Egyptian Chlorosis
Tunnel Anaemia	Dochmiosis
Necatorosis	African Cachexia
Water Itch Anaemia	Infection Due To Necator Americanus
St Gotthard Disease	Gotthard Tunnel Disease

Esophageal Adenosquamous Carcinoma

Western Equine Encephalitis

Western Equine Encephalomyelitis	Wee
Encephalomyelitis, Western Equine	Western Equine Encephalitis Virus Infection
Wee - [Western Equine Encephalitis]	Western Equine Encephalitis Virus

Autoimmune Optic Neuritis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08867	MXRA8 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MXRA8	VGNC	VGNC:107587
Bos taurus	MXRA8	VGNC	VGNC:50222
Macaca mulatta	MXRA8	VGNC	VGNC:75088
Mus musculus	MXRA8	MGD	MGI:1922011
Canis familiaris	MXRA8	VGNC	VGNC:53426
Rattus norvegicus	MXRA8	RGD	RGD:1359356
Others	MXRA8	NCBI

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