ARGLU1 - arginine and glutamate rich 1 Gene

Homo sapiens

Gene ID: 55082 | Gene type: protein coding

About ARGLU1

Cytogenetic location: 13q33.3 Genomic coordinates (GRCh38): 13:106,541,673-106,568,137 (from NCBI)

This gene has 4 transcripts (splice variants) and 210 orthologues. Ubiquitous expression in lung (RPKM 83.2), spleen (RPKM 81.9) and 25 other tissues.

Summary

Enables cadherin binding activity. Located in cytosol; mitochondrion; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ARGLU1 Products(1)

mRNA	Protein	Name
NM_018011.4	NP_060481.3	arginine and glutamate-rich protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables nuclear receptor coactivator activity	IMP IMP: Inferred from mutant phenotype	30698747	GOA
enables pre-mRNA binding	IDA IDA: Inferred from direct assay	30698747	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	22365833	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in regulation of alternative mRNA splicing, via spliceosome	IMP IMP: Inferred from mutant phenotype	30698747	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in nuclear speck	IDA IDA: Inferred from direct assay	30698747	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ARGLU1 Protein Structure

ARGLU

0
100
200
273 a.a.

Protein Preferred Names

Protein Names

arginine and glutamate-rich protein 1

ARGLU1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	ARGLU1	Q9NWB6	PUF60	Homo sapiens	Q9UHX1	Anti Tag CoIP	30698747
Intra	ARGLU1	Q9NWB6	PUF60	Homo sapiens	Q9UHX1	Confocal	30698747
Intra	ARGLU1	Q9NWB6	SRPK2	Homo sapiens	P78362	Protein Kinase Assay	23602568
Intra	ARGLU1	Q9NWB6	JMJD6	Homo sapiens	Q6NYC1	Anti Tag CoIP	30698747
Intra	ARGLU1	Q9NWB6	JMJD6	Homo sapiens	Q6NYC1	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Conventional Angiosarcoma

Brain Small Vessel Disease 2

Porencephaly 2	BSVD2
Gould Syndrome 2	Porencephaly 2, Formerly
Poren2, Formerly	Poren2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00910	ARGLU1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ARGLU1	MGD	MGI:2442985
Bos taurus	ARGLU1	VGNC	VGNC:26072
Rattus norvegicus	ARGLU1	RGD	RGD:1310061
Macaca mulatta	ARGLU1	VGNC	VGNC:106250
Felis catus	ARGLU1	VGNC	VGNC:59873
Canis familiaris	ARGLU1	VGNC	VGNC:38043

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