1. Gene
  2. HEMGN - hemogen Gene

HEMGN - hemogen Gene

Homo sapiens

Also known as NDR; EDAG; CT155; EDAG-1

Gene ID: 55363 | Gene type: protein coding

About HEMGN

Cytogenetic location: 9q22.33 Genomic coordinates (GRCh38): 9:97,926,791-97,944,852 (from NCBI)

This gene has 2 transcripts (splice variants) and 88 orthologues. Biased expression in bone marrow (RPKM 77.2) and testis (RPKM 23.8).

Summary

Predicted to be involved in regulation of osteoblast differentiation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

HEMGN Products(2)

mRNA Protein Name
NM_018437.5 NP_060907.2 hemogen
NM_197978.3 NP_932095.1 hemogen
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21988832 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hemogen

erythroid differentiation-associated gene protein

HEMGN Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
HEMGN Q9BXL5 NPM1 Homo sapiens P06748 22712502
Intra
HEMGN Q9BXL5 NPM1 Homo sapiens P06748
IF
22712502
Intra
HEMGN Q9BXL5 NPM1 Homo sapiens P06748 22712502
Intra
HEMGN Q9BXL5 CTBP1 Homo sapiens Q13363 21988832
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Colorectal Cancer, Hereditary Nonpolyposis, Type 2

HNPCC2

Fcc2

Coca2

Hereditary Nonpolyposis Colorectal Cancer Type 2

Colon Cancer, Familial Nonpolyposis, Type 2

Familial Nonpolyposis Colon Cancer Type 2

Hereditary Non-Polyposis Colorectal Cancer 2

Cancer, Colorectal, Nonpolyposis, Hereditary, Type 2

Panhypopituitarism, X-Linked

PHPX

X-Linked Panhypopituitarism

Pituitary Dwarfism Iv

Panhypopituitarism X-Linked

Pituitary Dwarfism Iv, Formerly

Panhypopituitarism - X-Linked

Ectodermal Dysplasia 1, Hypohidrotic, X-Linked

Christ-Siemens-Touraine Syndrome

XHED

Ectodermal Dysplasia 1

Xlhed

Ed1

Cst Syndrome

Ectodermal Dysplasia 1, Hypohidrotic/Hair/Tooth Type, X-Linked

Ectd1

Ectodermal Dysplasia, Anhidrotic, X-Linked

Eda

Eda1

Hed1

Ectodermal Dysplasia 1, Anhidrotic

X-Linked Anhidrotic Ectodermal Dysplasia

X-Linked Hypohidrotic Ectodermal Dysplasia

Hypohidrotic X-Linked Ectodermal Dysplasia

Ectodermal Dysplasia, Hypohidrotic, 1

Hypohidrotic Ectodermal Dysplasia, X-Linked

Anhidrotic Ectodermal Dysplasia X-Linked

Hypohidrotic Ectodermal Dysplasia X-Linked

Ectodermal Dysplasia 1 Hypohidrotic/Hair/Tooth Type X-Linked

Ectodermal Dysplasia Anhidrotic

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta HEMGN VGNC VGNC:73186
Mus musculus HEMGN MGD MGI:2136910
Felis catus HEMGN VGNC VGNC:62793
Bos taurus HEMGN VGNC VGNC:29807
Canis familiaris HEMGN VGNC VGNC:41654
Rattus norvegicus HEMGN RGD RGD:621569