Ywhag - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma Gene

Rattus norvegicus

Also known as 14-3-3G

Gene ID: 56010 | Gene type: protein coding

About Ywhag

Summary

Enables receptor tyrosine kinase binding activity. Involved in cellular response to Insulin stimulus. Located in vesicle. Is active in presynapse. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 56. Orthologous to human YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma). [provided by Alliance of Genome Resources, Apr 2022]

Ywhag Products(1)

mRNA	Protein	Name
NM_019376.2	NP_062249.1	14-3-3 protein gamma

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21454690	RGD
enables receptor tyrosine kinase binding	IPI IPI: Inferred from physical interaction	15604144	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to insulin stimulus	IDA IDA: Inferred from direct assay	21454690	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in presynapse	IDA IDA: Inferred from direct assay	16982421	RGD
is active in synapse	IDA IDA: Inferred from direct assay	7964746	RGD
located in vesicle	IDA IDA: Inferred from direct assay	21454690	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

14-3-3 protein gamma

14-3-3 protein gamma-subtype	3-monooxygenase/tryptophan 5-monooxgenase activation protein gamma polypeptide
tryosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein gamma	tryosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein

Ywhag Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Cross	Ywhag	P61983	LRRK2	Homo sapiens	Q5S007	Pull Down	24351927

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15942	YWHAG Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS15942A	YWHAG Human Pre-designed siRNA Set A-3		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ywhag	NCBI	NCBI:7532

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