YWHAG - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma Gene

Homo sapiens

Also known as DEE56; EIEE56; PPP1R170; 14-3-3GAMMA

Gene ID: 7532 | Gene type: protein coding

About YWHAG

Cytogenetic location: 7q11.23 Genomic coordinates (GRCh38): 7:76,326,799-76,358,991 (from NCBI)

This gene has 1 transcript (splice variant), 279 orthologues, 6 paralogues and is associated with 3 phenotypes. Broad expression in brain (RPKM 260.6), fat (RPKM 131.1) and 22 other tissues.

Summary

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both Plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]

YWHAG Products(1)

mRNA	Protein	Name
NM_012479.4	NP_036611.2	2014/3/3 protein gamma

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	17085597	GOA
enables insulin-like growth factor receptor binding	IPI IPI: Inferred from physical interaction	12482592	GOA
enables phosphorylation-dependent protein binding	IDA IDA: Inferred from direct assay	36732624	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	10559254	GOA
enables protein kinase C binding	IPI IPI: Inferred from physical interaction	10433554	GOA
enables protein sequestering activity	IDA IDA: Inferred from direct assay	36732624	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to glucose starvation	IDA IDA: Inferred from direct assay	36732624	GOA
involved in negative regulation of TORC1 signaling	IDA IDA: Inferred from direct assay	36732624	GOA
involved in positive regulation of T cell activation	IDA IDA: Inferred from direct assay	38377992	GOA
involved in positive regulation of T cell mediated immune response to tumor cell	IDA IDA: Inferred from direct assay	38377992	GOA
involved in positive regulation of cell-cell adhesion	IMP IMP: Inferred from mutant phenotype	29678907	GOA
involved in regulation of neuron differentiation	IMP IMP: Inferred from mutant phenotype	11824616	GOA
involved in regulation of protein localization	IMP IMP: Inferred from mutant phenotype	29678907	GOA
involved in regulation of synaptic plasticity	IMP IMP: Inferred from mutant phenotype	11824616	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytosol	IDA IDA: Inferred from direct assay	31906564	GOA
located in nucleus	IDA IDA: Inferred from direct assay	31906564	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

YWHAG Protein Structure

14-3-3

0
100
200
247 a.a.

Protein Preferred Names

Protein Names

14-3-3 protein gamma

KCIP-1

YWHAG Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	YWHAG	P61981	HSF2	Homo sapiens	Q03933-2	Validated Y2H	32814053
Intra	YWHAG	P61981	HSF2	Homo sapiens	Q03933-2	Y2H Pooling	32814053
Intra	YWHAG	P61981	HSF2	Homo sapiens	Q03933-2	Y2H Array	32814053
Intra	YWHAG	P61981	SAMD4A	Homo sapiens	Q9UPU9	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	SAMD4A	Homo sapiens	Q9UPU9	Anti Bait CoIP	17353931
Intra	YWHAG	P61981	SAMD4A	Homo sapiens	Q9UPU9	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	SAMD4A	Homo sapiens	Q9UPU9	BioID	36931259
Intra	YWHAG	P61981	PTPN3	Homo sapiens	P26045	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	PTPN3	Homo sapiens	P26045	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	PTPN3	Homo sapiens	P26045	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	PTPN3	Homo sapiens	P26045	Anti Bait CoIP	17353931
Intra	YWHAG	P61981	SH3BP4	Homo sapiens	Q9P0V3	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	SH3BP4	Homo sapiens	Q9P0V3	Anti Bait CoIP	17353931
Intra	YWHAG	P61981	SH3BP4	Homo sapiens	Q9P0V3	BioID	36931259
Intra	YWHAG	P61981	SH3BP4	Homo sapiens	Q9P0V3	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	SH3BP4	Homo sapiens	Q9P0V3	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	SH3BP4	Homo sapiens	Q9P0V3	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	CDC25B	Homo sapiens	P30305	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	CDC25B	Homo sapiens	P30305	CoIP	16672277
Intra	YWHAG	P61981	CDC25B	Homo sapiens	P30305	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	CDC25B	Homo sapiens	P30305	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	EPB41L2	Homo sapiens	O43491	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	EPB41L2	Homo sapiens	O43491	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	EPB41L2	Homo sapiens	O43491	Anti Bait CoIP	17353931
Intra	YWHAG	P61981	EPB41L2	Homo sapiens	O43491	BioID	36931259
Intra	YWHAG	P61981	IGBP1	Homo sapiens	P78318	Validated Y2H	32814053
Intra	YWHAG	P61981	IGBP1	Homo sapiens	P78318	Y2H Pooling	32814053
Intra	YWHAG	P61981	IGBP1	Homo sapiens	P78318	Y2H Array	32814053
Intra	YWHAG	P61981	WWOX	Homo sapiens	Q9NZC7-5	Y2H Pooling	32814053
Intra	YWHAG	P61981	WWOX	Homo sapiens	Q9NZC7-5	Validated Y2H	32814053
Intra	YWHAG	P61981	WWOX	Homo sapiens	Q9NZC7-5	Y2H Array	32814053
Intra	YWHAG	P61981	CENPV	Homo sapiens	Q7Z7K6	Validated Y2H	32814053
Intra	YWHAG	P61981	CENPV	Homo sapiens	Q7Z7K6	Y2H Pooling	32814053
Intra	YWHAG	P61981	CENPV	Homo sapiens	Q7Z7K6	Y2H Array	32814053
Intra	YWHAG	P61981	SDHC	Homo sapiens	Q99643	Validated Y2H	32814053
Intra	YWHAG	P61981	SDHC	Homo sapiens	Q99643	Y2H Pooling	32814053
Intra	YWHAG	P61981	SDHC	Homo sapiens	Q99643	Y2H Array	32814053
Intra	YWHAG	P61981	GRB10	Homo sapiens	Q13322-4	Y2H Pooling	32814053
Intra	YWHAG	P61981	GRB10	Homo sapiens	Q13322-4	Validated Y2H	32814053
Intra	YWHAG	P61981	GRB10	Homo sapiens	Q13322-4	Y2H Array	32814053
Intra	YWHAG	P61981	MAP3K6	Homo sapiens	O95382	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	MAP3K6	Homo sapiens	O95382	CoIP	19935702
Intra	YWHAG	P61981	MED19	Homo sapiens	A0JLT2-2	Y2H Array	32814053
Intra	YWHAG	P61981	MED19	Homo sapiens	A0JLT2-2	Validated Y2H	32814053
Intra	YWHAG	P61981	MED19	Homo sapiens	A0JLT2-2	Y2H Pooling	32814053
Intra	YWHAG	P61981	KLC3	Homo sapiens	Q6P597	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	KLC3	Homo sapiens	Q6P597	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	KIF1C	Homo sapiens	O43896	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	KIF1C	Homo sapiens	O43896	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	KIF1C	Homo sapiens	O43896	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	KIF1C	Homo sapiens	O43896	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	FAM53C	Homo sapiens	Q9NYF3	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	FAM53C	Homo sapiens	Q9NYF3	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	FAM53C	Homo sapiens	Q9NYF3	Validated Y2H	25416956
Intra	YWHAG	P61981	FAM53C	Homo sapiens	Q9NYF3	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	FAM53C	Homo sapiens	Q9NYF3	Y2H Pooling	20936779
Intra	YWHAG	P61981	FAM53C	Homo sapiens	Q9NYF3	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	IL3RA	Homo sapiens	P26951	Validated Y2H	32814053
Intra	YWHAG	P61981	IL3RA	Homo sapiens	P26951	Y2H Array	32814053
Intra	YWHAG	P61981	IL3RA	Homo sapiens	P26951	Y2H Pooling	32814053
Intra	YWHAG	P61981	CPN1	Homo sapiens	P15169	Validated Y2H	32814053
Intra	YWHAG	P61981	CPN1	Homo sapiens	P15169	Y2H Pooling	32814053
Intra	YWHAG	P61981	CPN1	Homo sapiens	P15169	Y2H Array	32814053
Intra	YWHAG	P61981	RCC1L	Homo sapiens	Q96I51	Y2H Pooling	32814053
Intra	YWHAG	P61981	RCC1L	Homo sapiens	Q96I51	Validated Y2H	32814053
Intra	YWHAG	P61981	RCC1L	Homo sapiens	Q96I51	Y2H Array	32814053
Intra	YWHAG	P61981	MACIR	Homo sapiens	Q96GV9	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	MACIR	Homo sapiens	Q96GV9	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	MACIR	Homo sapiens	Q96GV9	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	SNX33	Homo sapiens	Q8WV41	Y2H Pooling	32814053
Intra	YWHAG	P61981	SNX33	Homo sapiens	Q8WV41	Validated Y2H	32814053
Intra	YWHAG	P61981	SNX33	Homo sapiens	Q8WV41	Y2H Array	32814053
Intra	YWHAG	P61981	MPHOSPH9	Homo sapiens	Q99550	Y2H Pooling	20936779
Intra	YWHAG	P61981	MPHOSPH9	Homo sapiens	Q99550	BioID	36931259
Intra	YWHAG	P61981	HIVEP2	Homo sapiens	P31629	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	HIVEP2	Homo sapiens	P31629	BioID	36931259
Intra	YWHAG	P61981	HIVEP2	Homo sapiens	P31629	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	ANKHD1	Homo sapiens	Q8IWZ3-3	Y2H Pooling	32814053
Intra	YWHAG	P61981	ANKHD1	Homo sapiens	Q8IWZ3-3	Validated Y2H	32814053
Intra	YWHAG	P61981	ANKHD1	Homo sapiens	Q8IWZ3-3	Y2H Array	32814053
Intra	YWHAG	P61981	SP2	Homo sapiens	Q9BRW5	Validated Y2H	32814053
Intra	YWHAG	P61981	SP2	Homo sapiens	Q9BRW5	Y2H Pooling	32814053
Intra	YWHAG	P61981	SP2	Homo sapiens	Q9BRW5	Y2H Array	32814053
Intra	YWHAG	P61981	RMND1	Homo sapiens	Q9NWS8-3	Y2H Array	32814053
Intra	YWHAG	P61981	RMND1	Homo sapiens	Q9NWS8-3	Y2H Pooling	32814053
Intra	YWHAG	P61981	RMND1	Homo sapiens	Q9NWS8-3	Validated Y2H	32814053
Intra	YWHAG	P61981	GPR160	Homo sapiens	Q9UJ42	Validated Y2H	32814053
Intra	YWHAG	P61981	GPR160	Homo sapiens	Q9UJ42	Y2H Array	32814053
Intra	YWHAG	P61981	GPR160	Homo sapiens	Q9UJ42	Y2H Pooling	32814053
Intra	YWHAG	P61981	GNB5	Homo sapiens	Q96F32	Validated Y2H	32814053
Intra	YWHAG	P61981	GNB5	Homo sapiens	Q96F32	Y2H Array	32814053
Intra	YWHAG	P61981	GNB5	Homo sapiens	Q96F32	Y2H Pooling	32814053
Intra	YWHAG	P61981	MNDA	Homo sapiens	P41218	Validated Y2H	32814053
Intra	YWHAG	P61981	MNDA	Homo sapiens	P41218	Y2H Pooling	32814053
Intra	YWHAG	P61981	MNDA	Homo sapiens	P41218	Y2H Array	32814053
Intra	YWHAG	P61981	NHSL2	Homo sapiens	Q5HYW2	Validated Y2H	32296183
Intra	YWHAG	P61981	KRT18	Homo sapiens	P05783	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	KRT18	Homo sapiens	P05783	Y2H Pooling	20936779
Intra	YWHAG	P61981	MAPK11	Homo sapiens	Q15759	Validated Y2H	32814053
Intra	YWHAG	P61981	MAPK11	Homo sapiens	Q15759	Y2H Array	32814053
Intra	YWHAG	P61981	MAPK11	Homo sapiens	Q15759	Y2H Pooling	32814053
Intra	YWHAG	P61981	KIF23	Homo sapiens	Q02241	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	KIF23	Homo sapiens	Q02241	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	KIF23	Homo sapiens	Q02241	Pull Down	20451386
Intra	YWHAG	P61981	KIF23	Homo sapiens	Q02241	Anti Bait CoIP	17353931
Intra	YWHAG	P61981	KIF23	Homo sapiens	Q02241	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	KIF23	Homo sapiens	Q02241	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	KIF23	Homo sapiens	Q02241	BioID	36931259
Intra	YWHAG	P61981	MAP3K3	Homo sapiens	Q99759	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	MAP3K3	Homo sapiens	Q99759	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	MAP3K3	Homo sapiens	Q99759	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	HDAC4	Homo sapiens	P56524	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	HDAC4	Homo sapiens	P56524	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	HDAC4	Homo sapiens	P56524	Y2H Prey Pooling	25416956
Intra	YWHAG	P61981	HDAC4	Homo sapiens	P56524	BioID	36931259
Intra	YWHAG	P61981	HDAC4	Homo sapiens	P56524	CoIP	18045992
Intra	YWHAG	P61981	HDAC4	Homo sapiens	P56524	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	HDAC4	Homo sapiens	P56524	Anti Bait CoIP	17353931
Intra	YWHAG	P61981	HDAC4	Homo sapiens	P56524	Y2H Array	25416956
Intra	YWHAG	P61981	EPB41L3	Homo sapiens	Q9Y2J2	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	EPB41L3	Homo sapiens	Q9Y2J2	BioID	36931259
Intra	YWHAG	P61981	EPB41L3	Homo sapiens	Q9Y2J2	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	CGNL1	Homo sapiens	Q0VF96	Y2H Pooling	20936779
Intra	YWHAG	P61981	CGNL1	Homo sapiens	Q0VF96	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	CGNL1	Homo sapiens	Q0VF96	BioID	36931259
Intra	YWHAG	P61981	CGNL1	Homo sapiens	Q0VF96	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	CRTC3	Homo sapiens	Q6UUV7	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	CRTC3	Homo sapiens	Q6UUV7	BioID	36931259
Intra	YWHAG	P61981	CRTC3	Homo sapiens	Q6UUV7	Y2H Pooling	20936779
Intra	YWHAG	P61981	CRTC3	Homo sapiens	Q6UUV7	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	CRTC3	Homo sapiens	Q6UUV7	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	SRSF10	Homo sapiens	O75494	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	SRSF10	Homo sapiens	O75494	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	SRSF10	Homo sapiens	O75494	BioID	36931259
Intra	YWHAG	P61981	SRSF10	Homo sapiens	O75494	Anti Bait CoIP	17353931
Intra	YWHAG	P61981	YWHAE	Homo sapiens	P62258	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	YWHAE	Homo sapiens	P62258	Y2H Array	21988832
Intra	YWHAG	P61981	YWHAE	Homo sapiens	P62258	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	YWHAE	Homo sapiens	P62258	SLCA	17085597
Intra	YWHAG	P61981	YWHAE	Homo sapiens	P62258	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	YWHAE	Homo sapiens	P62258	BioID	36931259
Intra	YWHAG	P61981	YWHAE	Homo sapiens	P62258	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	PDCD2	Homo sapiens	Q16342	Validated Y2H	32814053
Intra	YWHAG	P61981	PDCD2	Homo sapiens	Q16342	Y2H Array	32814053
Intra	YWHAG	P61981	PDCD2	Homo sapiens	Q16342	Y2H Pooling	32814053
Intra	YWHAG	P61981	YWHAB	Homo sapiens	P31946	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	YWHAB	Homo sapiens	P31946	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	YWHAB	Homo sapiens	P31946	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	YWHAQ	Homo sapiens	P27348	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	YWHAQ	Homo sapiens	P27348	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	YWHAQ	Homo sapiens	P27348	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	YWHAQ	Homo sapiens	P27348	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	RAF1	Homo sapiens	P04049	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	RAF1	Homo sapiens	P04049	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	RAF1	Homo sapiens	P04049	Anti Bait CoIP	17353931
Intra	YWHAG	P61981	RAF1	Homo sapiens	P04049	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	RAF1	Homo sapiens	P04049	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	RAF1	Homo sapiens	P04049	BioID	36931259
Intra	YWHAG	P61981	TP53	Homo sapiens	P04637	CoIP	19933256
Intra	YWHAG	P61981	CIB1	Homo sapiens	Q99828	Validated Y2H	32814053
Intra	YWHAG	P61981	CIB1	Homo sapiens	Q99828	Y2H Pooling	32814053
Intra	YWHAG	P61981	CIB1	Homo sapiens	Q99828	Y2H Array	32814053
Intra	YWHAG	P61981	CEP95	Homo sapiens	Q96GE4	Y2H Pooling	20936779
Intra	YWHAG	P61981	CEP95	Homo sapiens	Q96GE4	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	CEP95	Homo sapiens	Q96GE4	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	CEP95	Homo sapiens	Q96GE4	BioID	36931259
Intra	YWHAG	P61981	ABL1	Homo sapiens	P00519	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	ABL1	Homo sapiens	P00519	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	ABL1	Homo sapiens	P00519	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	ABL1	Homo sapiens	P00519	BioID	36931259
Intra	YWHAG	P61981	RIMS3	Homo sapiens	Q9UJD0	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	RIMS3	Homo sapiens	Q9UJD0	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	MAP3K9	Homo sapiens	P80192	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	MDM4	Homo sapiens	O15151	Anti Tag CoIP	16511572
Intra	YWHAG	P61981	MDM4	Homo sapiens	O15151	Anti Bait CoIP	16511572
Intra	YWHAG	P61981	STIM1	Homo sapiens	Q13586	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	STIM1	Homo sapiens	Q13586	Validated Y2H	32814053
Intra	YWHAG	P61981	STIM1	Homo sapiens	Q13586	Y2H Array	32814053
Intra	YWHAG	P61981	STIM1	Homo sapiens	Q13586	Y2H Pooling	32814053
Intra	YWHAG	P61981	STIM1	Homo sapiens	Q13586	BioID	36931259
Intra	YWHAG	P61981	WNK1	Homo sapiens	Q9H4A3	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	WNK1	Homo sapiens	Q9H4A3	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	WNK1	Homo sapiens	Q9H4A3	BioID	36931259
Intra	YWHAG	P61981	WNK1	Homo sapiens	Q9H4A3	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	GPRASP2	Homo sapiens	Q96D09	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	GPRASP2	Homo sapiens	Q96D09	Y2H Pooling	32814053
Intra	YWHAG	P61981	GPRASP2	Homo sapiens	Q96D09	Validated Y2H	32814053
Intra	YWHAG	P61981	GPRASP2	Homo sapiens	Q96D09	Y2H Array	32814053
Intra	YWHAG	P61981	MAP3K5	Homo sapiens	Q99683	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	MAP3K5	Homo sapiens	Q99683	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	MAP3K5	Homo sapiens	Q99683	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	MAP3K5	Homo sapiens	Q99683	CoIP	19935702
Intra	YWHAG	P61981	SFN	Homo sapiens	P31947	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	MARK2	Homo sapiens	Q7KZI7	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	MARK2	Homo sapiens	Q7KZI7	Anti Tag CoIP	16959763
Intra	YWHAG	P61981	MARK2	Homo sapiens	Q7KZI7	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	MARK2	Homo sapiens	Q7KZI7	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	MARK2	Homo sapiens	Q7KZI7	BioID	36931259
Intra	YWHAG	P61981	MARK2	Homo sapiens	Q7KZI7	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	CBL	Homo sapiens	P22681	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	CBL	Homo sapiens	P22681	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	CBL	Homo sapiens	P22681	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	CBL	Homo sapiens	P22681	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	TNFAIP3	Homo sapiens	P21580	Y2H Pooling	20936779
Intra	YWHAG	P61981	TNFAIP3	Homo sapiens	P21580	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	KANK1	Homo sapiens	Q14678-2	Pull Down	18458160
Intra	YWHAG	P61981	KANK1	Homo sapiens	Q14678-2	Anti Tag CoIP	18458160
Intra	YWHAG	P61981	DRD1	Homo sapiens	P21728	Y2H Pooling	32814053
Intra	YWHAG	P61981	DRD1	Homo sapiens	P21728	Validated Y2H	32814053
Intra	YWHAG	P61981	DRD1	Homo sapiens	P21728	Y2H Array	32814053
Cross	YWHAG	P61981	Rnd3	Mus musculus	P61588	Anti Tag CoIP	23622247
Intra	YWHAG	P61981	BAD	Homo sapiens	Q92934	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	BAD	Homo sapiens	Q92934	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	BAD	Homo sapiens	Q92934	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	MARK3	Homo sapiens	P27448	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	MARK3	Homo sapiens	P27448	Anti Bait CoIP	17353931
Intra	YWHAG	P61981	MARK3	Homo sapiens	P27448	BioID	36931259
Intra	YWHAG	P61981	MARK3	Homo sapiens	P27448	Anti Tag CoIP	16959763
Intra	YWHAG	P61981	MARK3	Homo sapiens	P27448	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	MARK3	Homo sapiens	P27448	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	MARK3	Homo sapiens	P27448	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	IGFBP3	Homo sapiens	P17936	Validated Y2H	32814053
Intra	YWHAG	P61981	IGFBP3	Homo sapiens	P17936	Y2H Array	32814053
Intra	YWHAG	P61981	IGFBP3	Homo sapiens	P17936	Y2H Pooling	32814053
Intra	YWHAG	P61981	TINF2	Homo sapiens	Q9BSI4	Pull Down	21044950
Intra	YWHAG	P61981	TINF2	Homo sapiens	Q9BSI4	BiFC	21044950
Intra	YWHAG	P61981	NEDD4L	Homo sapiens	Q96PU5	BioID	36931259
Intra	YWHAG	P61981	NEDD4L	Homo sapiens	Q96PU5	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	NEDD4L	Homo sapiens	Q96PU5	Y2H Pooling	20936779
Intra	YWHAG	P61981	NEDD4L	Homo sapiens	Q96PU5	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	NEDD4L	Homo sapiens	Q96PU5	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	ZFP36L1	Homo sapiens	Q07352	BioID	36931259
Intra	YWHAG	P61981	ZFP36L1	Homo sapiens	Q07352	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	ITPRID2	Homo sapiens	P28290	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	ITPRID2	Homo sapiens	P28290	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	ITPRID2	Homo sapiens	P28290	BioID	36931259
Intra	YWHAG	P61981	ITPRID2	Homo sapiens	P28290	Y2H Pooling	20936779
Intra	YWHAG	P61981	TFAP2B	Homo sapiens	Q92481	Y2H Array	32814053
Intra	YWHAG	P61981	TFAP2B	Homo sapiens	Q92481	Validated Y2H	32814053
Intra	YWHAG	P61981	TFAP2B	Homo sapiens	Q92481	Y2H Pooling	32814053
Intra	YWHAG	P61981	WWTR1	Homo sapiens	Q9GZV5	Anti Tag CoIP	33961781
Intra	YWHAG	P61981	WWTR1	Homo sapiens	Q9GZV5	Anti Tag CoIP	28514442
Intra	YWHAG	P61981	WWTR1	Homo sapiens	Q9GZV5	Y2H Pooling	20936779
Intra	YWHAG	P61981	WWTR1	Homo sapiens	Q9GZV5	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	KLF12	Homo sapiens	Q9Y4X4	Validated Y2H	32814053
Intra	YWHAG	P61981	KLF12	Homo sapiens	Q9Y4X4	Y2H Array	32814053
Intra	YWHAG	P61981	KLF12	Homo sapiens	Q9Y4X4	Y2H Pooling	32814053
Intra	YWHAG	P61981	ACAP1	Homo sapiens	Q15027	Validated Y2H	32814053
Intra	YWHAG	P61981	ACAP1	Homo sapiens	Q15027	Y2H Pooling	32814053
Intra	YWHAG	P61981	ACAP1	Homo sapiens	Q15027	Y2H Array	32814053
Intra	YWHAG	P61981	GNA14	Homo sapiens	O95837	Y2H Array	32814053
Intra	YWHAG	P61981	GNA14	Homo sapiens	O95837	Y2H Pooling	32814053
Intra	YWHAG	P61981	GNA14	Homo sapiens	O95837	Validated Y2H	32814053
Intra	YWHAG	P61981	CENPJ	Homo sapiens	Q9HC77	CoIP	16516142
Intra	YWHAG	P61981	CENPJ	Homo sapiens	Q9HC77	Anti Tag CoIP	35271311
Intra	YWHAG	P61981	CENPJ	Homo sapiens	Q9HC77	Y2H Pooling	20936779
Intra	YWHAG	P61981	CHEK1	Homo sapiens	O14757	Anti Tag CoIP	36931259
Intra	YWHAG	P61981	CHEK1	Homo sapiens	O14757	Pull Down	20639859

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Developmental And Epileptic Encephalopathy 56

DEE56	Epileptic Encephalopathy, Early Infantile, 56
Eiee56	Developmental And Epileptic Encephalopathy, 56
Early Infantile Epileptic Encephalopathy 56

Constipation

Spasticity

Specific Learning Disability

Specific Learning Difficulty

Specific Learning Disorder

Hypotonia

Non-Specific Early-Onset Epileptic Encephalopathy

Undetermined Early-Onset Epileptic Encephalopathy	Non-Specific Eoee
Undetermined Eoee

Microcephaly

Microencephaly	Microcephalus
Microcephalic	Nanocephaly
Congenital Microcephaly	Brain Hypoplasia
Brain Nondevelopment	Cephalic Hypoplasia
Undeveloped Cerebrum	Undeveloped Brain
Micrencephalon	Micrencephaly

Developmental And Epileptic Encephalopathy

Encephalopathy, Developmental And Epileptic

Sudden Infant Death Syndrome

SIDS	Sudden Infant Death Syndrome, Susceptibility To
Cot Death	Crib Death
Sudden Death Of Nonspecific Cause In Infancy	Sudden Infant Death
Death, Sudden, Syndrome, Infant

Williams-Beuren Syndrome

Williams Syndrome	WBS
Wms	Deletion 7q11.23
Monosomy 7q11.23	Chromosome 7q11.23 Deletion Syndrome, 1.5- To 1.8-Mb
Fanconi Schlesinger Syndrome	Beuren Syndrome
Elfin Facies Syndrome	Elfin Facies With Hypercalcemia
Hypercalcemia-Supravalvar Aortic Stenosis	Ws

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15942	YWHAG Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS15942A	YWHAG Human Pre-designed siRNA Set A-3		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	YWHAG	VGNC	VGNC:48509
Rattus norvegicus	YWHAG	RGD	RGD:62002
Bos taurus	YWHAG	VGNC	VGNC:37046
Mus musculus	YWHAG	MGD	MGI:108109
Macaca mulatta	YWHAG	VGNC	VGNC:78820
Felis catus	YWHAG	VGNC	VGNC:67155

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