2. Gene
  3. Metap2 - methionine aminopeptidase 2 Gene

Metap2 - methionine aminopeptidase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p67; Amp2; Mnpep; p67eIF2; 4930584B20Rik; A930035J23Rik

Gene ID: 56307 | Gene type: protein coding

About Metap2

Summary

Predicted to enable Aminopeptidase activity and metalloexopeptidase activity. Predicted to be involved in N-terminal protein amino acid modification; peptidyl-methionine modification; and protein processing. Predicted to act upstream of or within proteolysis. Predicted to be located in cytosol and plasma membrane. Is expressed in brain and telencephalon. Orthologous to human METAP2 (methionyl Aminopeptidase 2). [provided by Alliance of Genome Resources, Apr 2022]

Metap2 Products(1)

mRNA Protein Name
NM_019648.3 NP_062622.1 methionine aminopeptidase 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15544353 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methionine aminopeptidase 2

MAP 2

eIF-2-associated p67

initiation factor 2-associated 67 kDa glycoprotein

initiation factor 2-associated protein (p67)

metAP 2

peptidase M 2

Recombinant Metap2 Proteins

Cat. No. Product Name Accession Purity
HY-P75925 METAP2/Methionine aminopeptidase 2 Protein, Mouse (sf9, His) O08663 (A2-Y478) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-14811 Beloranib Inhibitor / Phase 3
HY-114196 Aclimostat Inhibitor ≥98.0% Phase 2
HY-133016 M8891 Inhibitor 98.97% Phase 1
HY-13731 PPI-2458 Inhibitor 99.67% Phase 1
Pre-clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120868 TP-004 Inhibitor 98.89% Unkown
HY-134183 AUTAC1 Inducer ≥95.0% Unkown
HY-128147 MetAP-2-IN-6 Inhibitor 99.55% Unkown
HY-161742 Fumagilin-105 Inducer 97.34% Unkown
HY-P4344 Met-Gly-Pro-AMC Inhibitor 99.69% Unkown
HY-133016A (R)-M8891 Inhibitor 98.67% Unkown
HY-150409 TSPO ligand-2 99.63% Unkown
HY-161743 PBA-1105 Inducer / Unkown
HY-109188 Relzomostat Inhibitor / Unkown
HY-14811A Beloranib hemioxalate Inhibitor / Unkown
HY-158006 SDX-7539 Inhibitor / Unkown
HY-161744 PBA-1106 Inducer / Unkown
HY-161745 PBA-1105b / Unkown
HY-161746 Anle138b-F105 / Unkown
HY-RS08350 METAP2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Metap2 NCBI NCBI:10988