2. Gene
  3. PSKH1 - protein serine kinase H1 Gene

PSKH1 - protein serine kinase H1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 5681 | Gene type: protein coding

About PSKH1

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:67,893,254-67,929,676 (from NCBI)

This gene has 3 transcripts (splice variants), 203 orthologues and 22 paralogues. Ubiquitous expression in testis (RPKM 16.5), ovary (RPKM 12.3) and 25 other tissues.

Summary

Predicted to enable protein kinase activity. Predicted to act upstream of or within determination of left/right symmetry; heart development; and protein phosphorylation. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

PSKH1 Products(1)

mRNA Protein Name
NM_006742.3 NP_006733.1 serine/threonine-protein kinase H1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
22939624 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PSKH1 Protein Structure

Pkinase

Pkinase: Protein kinase domain (98 - 355)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 424 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase H1

PSK-H1

PSKH1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
PSKH1 P11801 HSP90AB1 Homo sapiens P08238
Pull Down
32707033
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Joubert Syndrome 17

JBTS17

Joubert Syndrome, Type 17
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11290 PSKH1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PSKH1 RGD RGD:1304648
Bos taurus PSKH1 VGNC VGNC:33437
Mus musculus PSKH1 MGD MGI:3528383
Macaca mulatta PSKH1 VGNC VGNC:76438
Canis familiaris PSKH1 VGNC VGNC:45088
Felis catus PSKH1 VGNC VGNC:69104