2. Gene
  3. Cd86 - CD86 molecule Gene

Cd86 - CD86 molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as B7-2

Gene ID: 56822 | Gene type: protein coding

About Cd86

Summary

Enables signaling receptor binding activity. Involved in several processes, including defense response to other organism; negative regulation of T cell anergy; and positive regulation of activated T cell proliferation. Located in cell surface. Used to study adult T-cell leukemia and bronchiolitis obliterans. Biomarker of asthma; corneal disease; middle cerebral artery infarction; and orchitis. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; autoimmune disease (multiple); chronic lymphocytic leukemia; chronic obstructive pulmonary disease; and systemic scleroderma. Orthologous to human CD86 (CD86 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd86 Products(1)

mRNA Protein Name
NM_020081.2 NP_064466.1 T-lymphocyte activation antigen CD86 precursor
Protein Preferred Names Protein Names

T-lymphocyte activation antigen CD86

cd86 antigen

membrane glycoprotein

Recombinant Cd86 Proteins

Cat. No. Product Name Accession Purity
HY-P7636 B7-2/CD86 Protein, Rat (HEK293, His) O35531 (V29-K247) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-W016773 1,10-Decanediol 99.93% Phase 1
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99821 Ravagalimab Inhibitor 99.31% Phase 2
Pre-clinical Phase
Bioactive Molecules (13)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148980A Polyinosinic acid sodium / Unkown
HY-150749 ODN D-SL03 Inducer 99.82% Unkown
HY-150749A ODN D-SL03 sodium 99.82% Unkown
HY-148980 Polyinosinic acid / Unkown
HY-143410 Anti-inflammatory agent 16 Inhibitor / Unkown
HY-144675 LSD1-IN-13 Inhibitor / Unkown
HY-144675A LSD1-IN-13 hydrochloride Inhibitor / Unkown
HY-150740 ODN 21595 Inhibitor / Unkown
HY-150740A ODN 21595 sodium Inhibitor / Unkown
HY-152201 BTK-IN-18 Inhibitor / Unkown
HY-160227 ORN 06 Activator / Unkown
HY-161833 HSP90-IN-31 Inhibitor / Unkown
HY-RS02274 CD86 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd86 NCBI NCBI:942
Macaca fascicularis Cd86 NCBI NCBI:102147235
Mus musculus Cd86 NCBI NCBI:12524
Leporidae Cd86 NCBI
Macaca mulatta Cd86 NCBI NCBI:714390