2. Gene
  3. NMUR2 - neuromedin U receptor 2 Gene

NMUR2 - neuromedin U receptor 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FM4; FM-4; TGR1; NMU2R; TGR-1; NMU-R2

Gene ID: 56923 | Gene type: protein coding

About NMUR2

Cytogenetic location: 5q33.1 Genomic coordinates (GRCh38): 5:152,391,546-152,405,279 (from NCBI)

This gene has 2 transcripts (splice variants), 131 orthologues and 15 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008]

NMUR2 Products(1)

mRNA Protein Name
NM_020167.5 NP_064552.3 neuromedin-U receptor 2

NMUR2 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (62 - 327)

  • 0
  • 100
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  • 415 a.a.
Protein Preferred Names Protein Names

neuromedin-U receptor 2

G-protein coupled receptor FM-4

Related Diseases

Diseases Alias
Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

Obesity , Susceptibility To

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-145086 R-PSOP Inhibitor 99.90% Unkown
HY-RS09393 NMUR2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-124681 NY0116 / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris NMUR2 VGNC VGNC:43867
Felis catus NMUR2 VGNC VGNC:63842
Bos taurus NMUR2 VGNC VGNC:32141
Rattus norvegicus NMUR2 RGD RGD:621155
Mus musculus NMUR2 MGD MGI:2441765
Macaca mulatta NMUR2 VGNC VGNC:75189