2. Gene
  3. UTP3 - UTP3 small subunit processome component Gene

UTP3 - UTP3 small subunit processome component Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CRL1; CRLZ1; SAS10

Gene ID: 57050 | Gene type: protein coding

About UTP3

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:70,688,532-70,690,551 (from NCBI)

This gene has 1 transcript (splice variant), 174 orthologues and 1 paralogue.

Summary

Enables RNA binding activity. Predicted to be involved in brain development and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

UTP3 Products(1)

mRNA Protein Name
NM_020368.3 NP_065101.1 something about silencing protein 10
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence Reference Source
involved in ribosomal small subunit biogenesis IDA
IDA: Inferred from direct assay
34516797 GOA
Cellular Component GO Annotation Evidence Reference Source
part of small-subunit processome IDA
IDA: Inferred from direct assay
34516797 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UTP3 Protein Structure

Sas10_Utp3

Sas10_Utp3: Sas10/Utp3/C1D family (229 - 310)

Sas10

Sas10: Sas10 C-terminal domain (404 - 478)

  • 0
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  • 400
  • 479 a.a.
Protein Preferred Names Protein Names

something about silencing protein 10

UTP3 homolog

Related Diseases

Diseases Alias
Palmoplantar Keratoderma, Bothnian Type

PPKB

Diffuse Palmoplantar Keratoderma, Bothnian Type

Bothnian Type Palmoplantar Keratoderma

Keratoderma, Palmoplantar, Bothnian Type

Palmoplantar Keratoderma, Nonepidermolytic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15579 UTP3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus UTP3 VGNC VGNC:36746
Felis catus UTP3 VGNC VGNC:66906
Canis familiaris UTP3 VGNC VGNC:48213
Macaca mulatta UTP3 VGNC VGNC:79434
Mus musculus UTP3 MGD MGI:1919230
Rattus norvegicus UTP3 RGD RGD:1308540