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  2. CYP20A1 - cytochrome P450 family 20 subfamily A member 1 Gene

CYP20A1 - cytochrome P450 family 20 subfamily A member 1 Gene

Homo sapiens

Also known as CYP-M

Gene ID: 57404 | Gene type: protein coding

About CYP20A1

This gene has 9 transcripts (splice variants) and 195 orthologues. Ubiquitous expression in thyroid (RPKM 2.4), kidney (RPKM 1.7) and 25 other tissues.

Summary

This gene encodes a member of the Cytochrome P450 superfamily of Enzymes. The Cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen. [provided by RefSeq, Jul 2008]

CYP20A1 Products(13)

mRNA Protein Name
NM_001371695.1 NP_001358624.1 cytochrome P450 20A1 isoform 1
NM_001371696.1 NP_001358625.1 cytochrome P450 20A1 isoform 3
NM_001371697.1 NP_001358626.1 cytochrome P450 20A1 isoform 3
NM_001371698.1 NP_001358627.1 cytochrome P450 20A1 isoform 3
NM_001371699.1 NP_001358628.1 cytochrome P450 20A1 isoform 6
NM_001371700.1 NP_001358629.1 cytochrome P450 20A1 isoform 4
NM_001371701.1 NP_001358630.1 cytochrome P450 20A1 isoform 4
NM_001371702.1 NP_001358631.1 cytochrome P450 20A1 isoform 5
NM_001371703.1 NP_001358632.1 cytochrome P450 20A1 isoform 5
NM_001371704.1 NP_001358633.1 cytochrome P450 20A1 isoform 5
NM_001371705.1 NP_001358634.1 cytochrome P450 20A1 isoform 5
NM_001371706.1 NP_001358635.1 cytochrome P450 20A1 isoform 5
NM_177538.3 NP_803882.1 cytochrome P450 20A1 isoform 2

CYP20A1 Protein Structure

p450

p450: Cytochrome P450 (43 - 446)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 462 a.a.
Protein Preferred Names Protein Names

cytochrome P450 20A1

cytochrome P450 monooxygenase

Related Diseases

Diseases Alias
Scabies

Sarcoptic Itch

Infestation By Sarcoptes Scabiei

Infestation By Sarcoptes Scabiei Var Hominis

Infestation By Sarcoptes Scabiei Var. Hominis

Keratomalacia

Vitamin A Deficiency

Night Blindness

Retinol Deficiency

Xerotic Keratitis

VAD

Vitamin A

Hypovitaminosis A

Bitot Spots

Bitot Spots In The Young Child

Conjunctival Xerosis With Bitot'S Spots

Vitamin A Deficiency With Cornea Xerosis

Vitamin A Deficiency With Cornea Ulceration Or Xerosis

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus CYP20A1 MGD MGI:1925201
Bos taurus CYP20A1 VGNC VGNC:110235
Rattus norvegicus CYP20A1 RGD RGD:735221
Macaca mulatta CYP20A1 VGNC VGNC:103631
Canis familiaris CYP20A1 VGNC VGNC:50351
Felis catus CYP20A1 VGNC VGNC:103335