2. Gene
  3. NYAP2 - neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 Gene

NYAP2 - neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as KIAA1486

Gene ID: 57624 | Gene type: protein coding

About NYAP2

Cytogenetic location: 2q36.3 Genomic coordinates (GRCh38): 2:225,397,939-225,703,654 (from NCBI)

This gene has 4 transcripts (splice variants), 257 orthologues and 1 paralogue. Low expression observed in reference dataset.

Summary

Predicted to be involved in neuron projection morphogenesis and phosphatidylinositol 3-kinase signaling. [provided by Alliance of Genome Resources, Apr 2022]

NYAP2 Products(2)

mRNA Protein Name
NM_001371273.1 NP_001358202.1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 isoform 1
NM_020864.2 NP_065915.1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 isoform 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NYAP2 Protein Structure

NYAP_N

NYAP_N: Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter (43 - 418)

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  • 653 a.a.
Protein Preferred Names Protein Names

neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

NYAP2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
NYAP2 Q9P242 MORN4 Homo sapiens Q8NDC4
Anti Tag CoIP
33961781
Intra
NYAP2 Q9P242 MORN4 Homo sapiens Q8NDC4
Validated Y2H
25416956
Intra
NYAP2 Q9P242 MORN4 Homo sapiens Q8NDC4
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Astigmatism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09722 NYAP2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NYAP2 VGNC VGNC:99389
Mus musculus NYAP2 MGD MGI:2443135
Felis catus NYAP2 VGNC VGNC:63942
Bos taurus NYAP2 VGNC VGNC:56133
Canis familiaris NYAP2 VGNC VGNC:44082
Rattus norvegicus NYAP2 RGD RGD:9171458