MORN4 - MORN repeat containing 4 Gene

Homo sapiens

Also known as UTA; rtp; C10orf83; bA548K23.4

Gene ID: 118812 | Gene type: protein coding

About MORN4

Cytogenetic location: 10q24.2 Genomic coordinates (GRCh38): 10:97,614,555-97,634,156 (from NCBI)

This gene has 3 transcripts (splice variants) and 220 orthologues. Broad expression in brain (RPKM 7.3), kidney (RPKM 3.8) and 23 other tissues.

Summary

Predicted to be involved in response to axon injury. Located in cytoplasm and filopodium tip. [provided by Alliance of Genome Resources, Apr 2022]

MORN4 Products(2)

mRNA	Protein	Name
NM_001098831.2	NP_001092301.1	MORN repeat-containing protein 4
NM_178832.4	NP_849154.1	MORN repeat-containing protein 4

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	25822849	GOA
located in filopodium tip	IDA IDA: Inferred from direct assay	25822849	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MORN4 Protein Structure

MORN

0
100
146 a.a.

Protein Preferred Names

Protein Names

MORN repeat-containing protein 4

44050 protein

MORN4 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	MORN4	Q8NDC4	CRTAC1	Homo sapiens	Q9NQ79	Y2H Array	25416956
Intra	MORN4	Q8NDC4	a0a384me25_human	Homo sapiens	A0A384ME25	Y2H Prey Pooling	25416956
Intra	MORN4	Q8NDC4	a0a384me25_human	Homo sapiens	A0A384ME25	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	a0a384me25_human	Homo sapiens	A0A384ME25	Y2H Array	25416956
Intra	MORN4	Q8NDC4	a0a384me25_human	Homo sapiens	A0A384ME25	Y2H Array	32296183
Intra	MORN4	Q8NDC4	a0a384me25_human	Homo sapiens	A0A384ME25	Validated Y2H	25416956
Intra	MORN4	Q8NDC4	ZNF131	Homo sapiens	P52739-2	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	ZNF131	Homo sapiens	P52739-2	Y2H Array	32296183
Intra	MORN4	Q8NDC4	FAM22F	Homo sapiens	B7ZLH0	Validated Y2H	25416956
Intra	MORN4	Q8NDC4	FAM22F	Homo sapiens	B7ZLH0	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	FAM22F	Homo sapiens	B7ZLH0	Y2H Array	25416956
Intra	MORN4	Q8NDC4	FAM22F	Homo sapiens	B7ZLH0	Y2H Array	32296183
Intra	MORN4	Q8NDC4	NYAP2	Homo sapiens	Q9P242	Y2H Prey Pooling	25416956
Intra	MORN4	Q8NDC4	TCF12	Homo sapiens	Q99081-3	Validated Y2H	32296183
Intra	MORN4	Q8NDC4	TCF12	Homo sapiens	Q99081-3	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	TCF12	Homo sapiens	Q99081-3	Y2H Array	32296183
Intra	MORN4	Q8NDC4	GUCD1	Homo sapiens	Q96NT3-2	Validated Y2H	32296183
Intra	MORN4	Q8NDC4	KRT25	Homo sapiens	Q7Z3Z0	Y2H Array	32296183
Intra	MORN4	Q8NDC4	KRT25	Homo sapiens	Q7Z3Z0	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	MAGI2	Homo sapiens	Q86UL8-2	Y2H Array	32296183
Intra	MORN4	Q8NDC4	MAGI2	Homo sapiens	Q86UL8-2	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	HMMR	Homo sapiens	O75330-3	Y2H Array	32296183
Intra	MORN4	Q8NDC4	HMMR	Homo sapiens	O75330-3	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	BEND3	Homo sapiens	Q5T5X7	Y2H Prey Pooling	25416956
Intra	MORN4	Q8NDC4	BEND3	Homo sapiens	Q5T5X7	Validated Y2H	25416956
Intra	MORN4	Q8NDC4	BEND3	Homo sapiens	Q5T5X7	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	BEND3	Homo sapiens	Q5T5X7	Y2H Array	32296183
Intra	MORN4	Q8NDC4	TCF4	Homo sapiens	P15884-3	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	TCF4	Homo sapiens	P15884-3	Y2H Array	32296183
Intra	MORN4	Q8NDC4	SYTL2	Homo sapiens	Q9HCH5-13	Validated Y2H	32296183
Intra	MORN4	Q8NDC4	SYTL2	Homo sapiens	Q9HCH5-13	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	SYTL2	Homo sapiens	Q9HCH5-13	Y2H Array	32296183
Intra	MORN4	Q8NDC4	SSX2IP	Homo sapiens	Q9Y2D8	Y2H Array	25416956
Intra	MORN4	Q8NDC4	SSX2IP	Homo sapiens	Q9Y2D8	Validated Y2H	25416956
Intra	MORN4	Q8NDC4	SSX2IP	Homo sapiens	Q9Y2D8	Validated Y2H	32296183
Intra	MORN4	Q8NDC4	SSX2IP	Homo sapiens	Q9Y2D8	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	SSX2IP	Homo sapiens	Q9Y2D8	Y2H Prey Pooling	25416956
Intra	MORN4	Q8NDC4	SSX2IP	Homo sapiens	Q9Y2D8	Y2H Array	32296183
Intra	MORN4	Q8NDC4	UEVLD	Homo sapiens	Q8IX04	Anti Tag CoIP	33961781
Intra	MORN4	Q8NDC4	DNAJC9	Homo sapiens	Q8WXX5	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	DNAJC9	Homo sapiens	Q8WXX5	Validated Y2H	32296183
Intra	MORN4	Q8NDC4	DNAJC9	Homo sapiens	Q8WXX5	Y2H Array	32296183
Intra	MORN4	Q8NDC4	HMMR	Homo sapiens	O75330	Y2H Array	31515488
Intra	MORN4	Q8NDC4	PLAGL2	Homo sapiens	Q9UPG8	Y2H Array	32296183
Intra	MORN4	Q8NDC4	PLAGL2	Homo sapiens	Q9UPG8	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	PLAGL2	Homo sapiens	Q9UPG8	Validated Y2H	32296183
Intra	MORN4	Q8NDC4	KRT27	Homo sapiens	Q7Z3Y8	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	KRT27	Homo sapiens	Q7Z3Y8	Y2H Array	32296183
Intra	MORN4	Q8NDC4	EXOSC8	Homo sapiens	Q96B26	Y2H Array	32296183
Intra	MORN4	Q8NDC4	EXOSC8	Homo sapiens	Q96B26	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	EXOSC8	Homo sapiens	Q96B26	Validated Y2H	32296183
Intra	MORN4	Q8NDC4	APOA5	Homo sapiens	Q6Q788	Y2H Array	32296183
Intra	MORN4	Q8NDC4	APOA5	Homo sapiens	Q6Q788	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	TCF4	Homo sapiens	P15884	Y2H Array	25416956
Intra	MORN4	Q8NDC4	RHOQ	Homo sapiens	P17081	Y2H Array	32296183
Intra	MORN4	Q8NDC4	RHOQ	Homo sapiens	P17081	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	WBP11	Homo sapiens	Q9Y2W2	Y2H Array	32296183
Intra	MORN4	Q8NDC4	WBP11	Homo sapiens	Q9Y2W2	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	WBP11	Homo sapiens	Q9Y2W2	Validated Y2H	32296183
Intra	MORN4	Q8NDC4	TCF12	Homo sapiens	Q99081	Y2H Prey Pooling	25416956
Intra	MORN4	Q8NDC4	TCF12	Homo sapiens	Q99081	Validated Y2H	25416956
Intra	MORN4	Q8NDC4	TCF12	Homo sapiens	Q99081	Y2H Array	25416956
Intra	MORN4	Q8NDC4	SNCB	Homo sapiens	Q16143	Y2H Array	32296183
Intra	MORN4	Q8NDC4	SNCB	Homo sapiens	Q16143	Y2H Pooling	32814053
Intra	MORN4	Q8NDC4	SNCB	Homo sapiens	Q16143	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	SNCB	Homo sapiens	Q16143	Validated Y2H	32814053
Intra	MORN4	Q8NDC4	SNCB	Homo sapiens	Q16143	Y2H Array	32814053
Intra	MORN4	Q8NDC4	TRIM23	Homo sapiens	P36406	Y2H Array	32296183
Intra	MORN4	Q8NDC4	TRIM23	Homo sapiens	P36406	Y2H Prey Pooling	25416956
Intra	MORN4	Q8NDC4	TRIM23	Homo sapiens	P36406	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	SEPTIN6	Homo sapiens	Q14141	Y2H Prey Pooling	25416956
Intra	MORN4	Q8NDC4	SEPTIN6	Homo sapiens	Q14141	Validated Y2H	25416956
Intra	MORN4	Q8NDC4	SEPTIN6	Homo sapiens	Q14141	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	SEPTIN6	Homo sapiens	Q14141	Y2H Array	25416956
Intra	MORN4	Q8NDC4	INO80E	Homo sapiens	Q8NBZ0	Validated Y2H	25416956
Intra	MORN4	Q8NDC4	TRIM44	Homo sapiens	Q96DX7	Y2H Prey Pooling	32296183
Intra	MORN4	Q8NDC4	TRIM44	Homo sapiens	Q96DX7	Validated Y2H	32296183
Intra	MORN4	Q8NDC4	TRIM44	Homo sapiens	Q96DX7	Y2H Array	32296183
Intra	MORN4	Q8NDC4	SEPTIN11	Homo sapiens	Q9NVA2	Validated Y2H	32296183
Intra	MORN4	Q8NDC4	SEPTIN11	Homo sapiens	Q9NVA2	Y2H Array	32296183
Intra	MORN4	Q8NDC4	SEPTIN11	Homo sapiens	Q9NVA2	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Deafness, Autosomal Recessive 30

DFNB30	Autosomal Recessive Nonsyndromic Deafness 30
Autosomal Recessive Deafness 30	Deafness, Autosomal Recessive, 30
Deafness, Autosomal Recessive, Type 30

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08596	MORN4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MORN4	VGNC	VGNC:63562
Mus musculus	MORN4	MGD	MGI:2449568
Macaca mulatta	MORN4	VGNC	VGNC:74815
Canis familiaris	MORN4	VGNC	VGNC:49797
Bos taurus	MORN4	VGNC	VGNC:31561
Rattus norvegicus	MORN4	RGD	RGD:1307336

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