2. Gene
  3. Angptl4 - angiopoietin-like 4 Gene

Angptl4 - angiopoietin-like 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Arp4; Bk89; Fiaf; Ng27; Pgar; Hfarp; Pgarg; Pp1158

Gene ID: 57875 | Gene type: protein coding

About Angptl4

Summary

Enables Enzyme inhibitor activity. Involved in negative regulation of apoptotic process; negative regulation of lipoprotein Lipase activity; and triglyceride homeostasis. Acts upstream of or within negative regulation of endothelial cell apoptotic process. Located in extracellular space. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; integumental system; and musculature. Orthologous to human ANGPTL4 (Angiopoietin Like 4). [provided by Alliance of Genome Resources, Apr 2022]

Angptl4 Products(1)

mRNA Protein Name
NM_020581.2 NP_065606.2 angiopoietin-related protein 4 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables enzyme inhibitor activity IDA
IDA: Inferred from direct assay
12401877 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of endothelial cell apoptotic process IDA
IDA: Inferred from direct assay
10698685 MGI
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
10698685 MGI
acts upstream of or within negative regulation of endothelial cell apoptotic process IDA
IDA: Inferred from direct assay
10698685 MGI
involved in negative regulation of lipoprotein lipase activity IDA
IDA: Inferred from direct assay
12401877 MGI
involved in triglyceride homeostasis IMP
IMP: Inferred from mutant phenotype
19542565 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular region IDA
IDA: Inferred from direct assay
10698685 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
10866690 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

angiopoietin-related protein 4

425O18-1

angiopoietin-like protein 4

fasting-induced adipose factor

fibrinogen/angiopoietin-related protein

hepatic fibrinogen/angiopoietin-related protein

major histocompatibility complex region NG27

secreted protein Bk89

Recombinant Angptl4 Proteins

Cat. No. Product Name Accession Purity
HY-P7508 ANGPTL4/Angiopoietin-related 4 Protein, Mouse (HEK293, Fc, solution) Q9Z1P8 (K167-S410) ≥95%
HY-P78237 ANGPTL4/Angiopoietin-related 4 Protein, Mouse (HEK293, His) Q9Z1P8 (R168-S410) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-116247 ST247 Agonist 99.88% Unkown
HY-RS00693 ANGPTL4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990335 Anti-ANGPTL4 Antibody / Unkown
HY-P990336 Anti-ANGPTL8 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Angptl4 NCBI NCBI:51129
Macaca fascicularis Angptl4 NCBI NCBI:102135390