2. Gene
  3. Cd14 - CD14 molecule Gene

Cd14 - CD14 molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 60350 | Gene type: protein coding

About Cd14

Summary

Predicted to enable Lipopeptide binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Involved in several processes, including cellular response to lipopolysaccharide; response to magnesium ion; and response to tumor necrosis factor. Located in cell surface; extracellular space; and plasma membrane. Used to study perinatal necrotizing enterocolitis. Biomarker of Hirschsprung's disease; cholestasis; obstructive jaundice; and periodontitis. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; artery disease (multiple); celiac disease; cystic fibrosis; and pulmonary tuberculosis. Orthologous to human CD14 (CD14 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd14 Products(1)

mRNA Protein Name
NM_021744.1 NP_068512.1 monocyte differentiation antigen CD14 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18787027 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
22511970 RGD
involved in positive regulation of cytokine production IMP
IMP: Inferred from mutant phenotype
12046090 RGD
involved in response to electrical stimulus IEP
IEP: Inferred from expression pattern
19464360 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
10414605 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
16631199 RGD
involved in response to magnesium ion IEP
IEP: Inferred from expression pattern
16180088 RGD
involved in response to tumor necrosis factor IMP
IMP: Inferred from mutant phenotype
10777809 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
12046090 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
12835948 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

monocyte differentiation antigen CD14

CD14 antigen

myeloid cell-specific leucine-rich glycoprotein

Recombinant Cd14 Proteins

Cat. No. Product Name Accession Purity
HY-P74331 CD14 Protein, Rat (HEK293, His) Q63691 (S18-Y341) ≥95%
HY-P74332 CD14 Protein, Rat (HEK293, Fc) Q63691 (M1-Y341) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-N9965 2'-Fucosyllactose Inhibitor 99.95% Phase 2
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-135750 VAF347 Agonist 99.90% Unkown
HY-101132 VB-201 / Unkown
HY-151399 Antimicrobial agent-5 Inhibitor / Unkown
HY-161901 BC-1293 Inhibitor / Unkown
HY-169067 10-Methoxy-canthin-6-one Activator / Unkown
HY-RS02189 CD14 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd14 NCBI NCBI:929
Canis familiaris Cd14 NCBI NCBI:607076
Macaca fascicularis Cd14 NCBI NCBI:102129342
Mus musculus Cd14 NCBI NCBI:12475
Leporidae Cd14 NCBI
Macaca mulatta Cd14 NCBI NCBI:697482