2. Gene
  3. Cd14 - CD14 antigen Gene

Cd14 - CD14 antigen Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 12475 | Gene type: protein coding

About Cd14

Summary

This gene encodes a protein that plays an important role in the innate immune response and is expressed in monocyte/macrophage cells. This gene product acts as a co-receptor that binds several microbial and Fungal molecules, including lipopolysaccharides (LPS). This proteins LPS-binding activity is enhanced by the LPS binding protein (LBP) to allow binding to the TLR4-MD-2 co-receptor complex. The product of this gene is found in two forms, either as a soluble protein or attached to the cell surface by a glycosylphosphatidylinositol anchor. [provided by RefSeq, Jul 2014]

Cd14 Products(1)

mRNA Protein Name
NM_009841.4 NP_033971.1 monocyte differentiation antigen CD14 precursor
Protein Preferred Names Protein Names

monocyte differentiation antigen CD14

myeloid cell-specific leucine-rich glycoprotein

Recombinant Cd14 Proteins

Cat. No. Product Name Accession Purity
HY-P73531 CD14 Protein, Mouse (HEK293, His) P10810/NP_033971.1 (S16-P345) ≥95%
HY-P75444 CD14 Protein, Mouse (HEK293, His-Fc) P10810/NP_033971.1 (S16-P345) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-N9965 2'-Fucosyllactose Inhibitor 99.95% Phase 2
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-135750 VAF347 Agonist 99.90% Unkown
HY-101132 VB-201 / Unkown
HY-151399 Antimicrobial agent-5 Inhibitor / Unkown
HY-161901 BC-1293 Inhibitor / Unkown
HY-169067 10-Methoxy-canthin-6-one Activator / Unkown
HY-RS02189 CD14 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd14 NCBI NCBI:929
Canis familiaris Cd14 NCBI NCBI:607076
Macaca fascicularis Cd14 NCBI NCBI:102129342
Leporidae Cd14 NCBI
Rattus norvegicus Cd14 NCBI NCBI:60350
Macaca mulatta Cd14 NCBI NCBI:697482