2. Gene
  3. Acss2 - acyl-CoA synthetase short-chain family member 2 Gene

Acss2 - acyl-CoA synthetase short-chain family member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ACS; ACAS; Acs1; Acas1; Acas2; aceCS; AceCS1; 1110017C11Rik

Gene ID: 60525 | Gene type: protein coding

About Acss2

Summary

Enables acetate-CoA Ligase activity and propionate-CoA Ligase activity. Acts upstream of or within acetyl-CoA biosynthetic process. Located in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; liver; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in orofacial cleft. Orthologous to human ACSS2 (acyl-CoA synthetase short chain family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Acss2 Products(1)

mRNA Protein Name
NM_019811.3 NP_062785.2 acetyl-coenzyme A synthetase, cytoplasmic
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables acetate-CoA ligase activity IDA
IDA: Inferred from direct assay
11150295 MGI
enables acetate-CoA ligase activity IMP
IMP: Inferred from mutant phenotype
28562591 MGI
enables chromatin binding IDA
IDA: Inferred from direct assay
28562591 MGI
enables propionate-CoA ligase activity IDA
IDA: Inferred from direct assay
11150295 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
28562591 MGI
enables transcription coactivator activity IMP
IMP: Inferred from mutant phenotype
28562591 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within acetyl-CoA biosynthetic process IDA
IDA: Inferred from direct assay
11150295 MGI
involved in long-term memory IMP
IMP: Inferred from mutant phenotype
28562591 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11150295 MGI
located in cytosol IDA
IDA: Inferred from direct assay
28552616 MGI
located in nucleus IDA
IDA: Inferred from direct assay
28552616 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acetyl-coenzyme A synthetase, cytoplasmic

acetate--CoA ligase

acetyl-CoA synthetase 1

acetyl-Coenzyme A synthetase 1 (AMP forming)

acetyl-Coenzyme A synthetase 2 (ADP forming)

acetyl-Coenzyme A synthetase 2 (AMP forming)

acyl-activating enzyme

propionate--CoA ligase

Recombinant Acss2 Proteins

Cat. No. Product Name Accession Purity
HY-P71642 Acetyl-CoA synthetase 1/AceCS Protein, Mouse (His) Q9QXG4 (M1-Q701) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-104032 Ac-CoA Synthase Inhibitor1 Inhibitor 99.33% Unkown
HY-145953 VY-3-135 Inhibitor 98.51% Unkown
HY-148104 ACSS2-IN-2 Inhibitor 98.06% Unkown
HY-145392 ACSS2-IN-1 Inhibitor / Unkown
HY-161116 AD-5584 / Unkown
HY-161117 AD-8007 / Unkown
HY-RS00211 ACSS2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acss2 NCBI NCBI:55902