NECAB1 - N-terminal EF-hand calcium binding protein 1 Gene

Homo sapiens

Also known as EFCBP1; STIP-1

Gene ID: 64168 | Gene type: protein coding

About NECAB1

This gene has 6 transcripts (splice variants), 188 orthologues and 2 paralogues. Biased expression in brain (RPKM 31.1), testis (RPKM 8.9) and 12 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in regulation of amyloid precursor protein biosynthetic process. Predicted to act upstream of or within blastocyst hatching. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NECAB1 Products(1)

mRNA	Protein	Name
NM_022351.5	NP_071746.1	N-terminal EF-hand calcium-binding protein 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NECAB1 Protein Structure

EF-hand_5

ABM

0
100
200
300
351 a.a.

Protein Preferred Names

Protein Names

N-terminal EF-hand calcium-binding protein 1

EF-hand calcium-binding protein 1

Related Diseases

Diseases

Alias

Motor Neuron Disease

Anterior Horn Cell Disease	Motor Neuron Diseases
Mnd - [Motor Neurone Disease]	Lou Gehrig Disease
Creeping Palsy	Creeping Paralysis
Bulbar Motor Neuron Disease	Bulbar Syndrome
Anterior Horn Cell Disorder	Hereditary Motor Neuron Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09170	NECAB1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	NECAB1	VGNC	VGNC:63762
Macaca mulatta	NECAB1	VGNC	VGNC:75223
Canis familiaris	NECAB1	VGNC	VGNC:43714
Mus musculus	NECAB1	MGD	MGI:1916602
Rattus norvegicus	NECAB1	RGD	RGD:708548

Name
Email *

	Sorry, but the email address you supplied was invalid.