2. Gene
  3. GNPNAT1 - glucosamine-phosphate N-acetyltransferase 1 Gene

GNPNAT1 - glucosamine-phosphate N-acetyltransferase 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GNA1; GNPNAT; Gpnat1; RHZDAN

Gene ID: 64841 | Gene type: protein coding

About GNPNAT1

Cytogenetic location: 14q22.1 Genomic coordinates (GRCh38): 14:52,775,193-52,791,607 (from NCBI)

This gene has 6 transcripts (splice variants) and 219 orthologues. Ubiquitous expression in liver (RPKM 17.9), colon (RPKM 9.0) and 25 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process. Predicted to act upstream of or within cellular response to Leukemia Inhibitory Factor. Predicted to be located in late endosome. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Apr 2022]

GNPNAT1 Products(1)

mRNA Protein Name
NM_198066.4 NP_932332.1 glucosamine 6-phosphate N-acetyltransferase
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
18675810 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GNPNAT1 Protein Structure

Acetyltransf_1

Acetyltransf_1: Acetyltransferase (GNAT) family (95 - 171)

  • 0
  • 100
  • 184 a.a.
Protein Preferred Names Protein Names

glucosamine 6-phosphate N-acetyltransferase

phosphoglucosamine acetylase

Related Diseases

Diseases Alias
Rhizomelic Dysplasia, Ain-Naz Type

RHZDAN
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05573 GNPNAT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GNPNAT1 MGD MGI:1858963
Macaca mulatta GNPNAT1 VGNC VGNC:72971
Canis familiaris GNPNAT1 VGNC VGNC:41333
Felis catus GNPNAT1 VGNC VGNC:62632
Bos taurus GNPNAT1 VGNC VGNC:29478
Rattus norvegicus GNPNAT1 RGD RGD:1563144