1. Gene
  2. NAGK - N-acetylglucosamine kinase Gene

NAGK - N-acetylglucosamine kinase Gene

Homo sapiens

Also known as GNK; HSA242910

Gene ID: 55577 | Gene type: protein coding

About NAGK

Cytogenetic location: 2p13.3 Genomic coordinates (GRCh38): 2:71,068,296-71,079,808 (from NCBI)

This gene has 29 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in spleen (RPKM 27.6), esophagus (RPKM 26.3) and 25 other tissues.

Summary

This gene encodes a member of the N-acetylhexosamine kinase family. The encoded protein catalyzes the conversion of N-acetyl-D-glucosamine to N-acetyl-D-glucosamine 6-phosphate, and is the major mammalian Enzyme which recovers amino sugars. [provided by RefSeq, Nov 2011]

NAGK Products(4)

mRNA Protein Name
NM_001330425.3 NP_001317354.1 N-acetyl-D-glucosamine kinase isoform 2
NM_001330426.2 NP_001317355.1 N-acetyl-D-glucosamine kinase isoform 2
NM_001365466.2 NP_001352395.1 N-acetyl-D-glucosamine kinase isoform 2
NM_017567.6 NP_060037.4 N-acetyl-D-glucosamine kinase isoform 1

NAGK Protein Structure

BcrAD_BadFG

BcrAD_BadFG: BadF/BadG/BcrA/BcrD ATPase family (7 - 278)

  • 0
  • 100
  • 200
  • 300
  • 344 a.a.
Protein Preferred Names Protein Names

N-acetyl-D-glucosamine kinase

epididymis secretory sperm binding protein

NAGK Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
NAGK Q9UJ70 ACTR10 Homo sapiens Q9NZ32 25416956
Intra
NAGK Q9UJ70 MEOX1 Homo sapiens P50221 25416956
Intra
NAGK Q9UJ70 MEOX1 Homo sapiens P50221 25416956
Intra
NAGK Q9UJ70 REL Homo sapiens Q04864 25416956
Intra
NAGK Q9UJ70 REL Homo sapiens Q04864 25416956
Intra
NAGK Q9UJ70 DACH1 Homo sapiens Q9UI36
Y2H
21516116
Intra
NAGK Q9UJ70 CDKN2C Homo sapiens P42773 31515488
Intra
NAGK Q9UJ70 CDKN2C Homo sapiens P42773 25416956
Intra
NAGK Q9UJ70 CDKN2C Homo sapiens P42773 25416956
Intra
NAGK Q9UJ70 TCF12 Homo sapiens Q99081 25416956
Intra
NAGK Q9UJ70 SDCBP Homo sapiens O00560 25416956
Intra
NAGK Q9UJ70 SDCBP Homo sapiens O00560 25416956
Intra
NAGK Q9UJ70 LNX1 Homo sapiens Q8TBB1 16189514
Intra
NAGK Q9UJ70 LNX1 Homo sapiens Q8TBB1 29892012
Intra
NAGK Q9UJ70 LNX1 Homo sapiens Q8TBB1 16189514
Cross
NAGK Q9UJ70 Snrpn Rattus norvegicus P63164 37511433
Cross
NAGK Q9UJ70 Snrpn Rattus norvegicus P63164 37511433
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Nonaka Myopathy

Gne Myopathy

Hibm

Distal Myopathy With Rimmed Vacuoles

Hereditary Inclusion Body Myopathy

Ibm2

Inclusion Body Myopathy, Quadriceps-Sparing

Qsm

Dmrv

Distal Myopathy, Nonaka Type

Inclusion Body Myopathy 2

Inclusion Body Myopathy, Autosomal Recessive

NM

Nonaka Distal Myopathy

Myopathy, Distal, With Or Without Rimmed Vacuoles

Inclusion Body Myopathy, Hereditary, Autosomal Recessive

Inclusion Body Myopathy Type 2

Quadriceps-Sparing Myopathy

Quadriceps Sparing Myopathy

Rimmed Vacuole Myopathy

Inclusion Body Myopathy 2, Autosomal Recessive, Formerly

Ibm2, Formerly

Hibm2

Hereditary Inclusion Body Myopathy Type 2

Inclusion Body Myopathy 2, Autosomal Recessive

Myopathy, Distal, With Rimmed Vacuoles

Inclusion Body Myopathy Autosomal Recessive

Myopathy, Inclusion Body, Type 2

Myopathy, Nonaka

Sialuria

Sialuria, French Type

French Type Sialuria

Sialuria French Type

Sialic Acid Storage Disease

Sialic Acid Storage Disease, Finnish Type

Infantile Sialic Acid Storage Disease

Chronic Monocytic Leukemia

Leukemia, Myeloid

Leukemia, Monocytic, Chronic

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus NAGK RGD RGD:1305057
Macaca mulatta NAGK VGNC VGNC:74977
Bos taurus NAGK VGNC VGNC:31868
Mus musculus NAGK MGD MGI:1860418
Felis catus NAGK VGNC VGNC:63713