2. Gene
  3. Tmem109 - transmembrane protein 109 Gene

Tmem109 - transmembrane protein 109 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 1110006I15Rik

Gene ID: 68539 | Gene type: protein coding

About Tmem109

Summary

Predicted to enable voltage-gated ion channel activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Predicted to be located in endoplasmic reticulum and nuclear membrane. Is expressed in central nervous system; early conceptus; retina; and secondary oocyte. Orthologous to human TMEM109 (transmembrane protein 109). [provided by Alliance of Genome Resources, Apr 2022]

Tmem109 Products(2)

mRNA Protein Name
NM_134142.1 NP_598903.1 transmembrane protein 109 precursor
NM_134142.1 NP_598903.1 transmembrane protein 109 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
23542032 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
IMP: Inferred from mutant phenotype
20060811 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane protein 109

mg23

mitsugumin-23

mitsugumin23

Tmem109 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Tmem109 Q3UBX0 CRYAB Homo sapiens P02511
Anti Tag CoIP
23542032
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14650 TMEM109 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem109 NCBI NCBI:79073