2. Gene
  3. BTF3 - basic transcription factor 3 Gene

BTF3 - basic transcription factor 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NACB; BTF3a; BTF3b; BETA-NAC

Gene ID: 689 | Gene type: protein coding

About BTF3

Cytogenetic location: 5q13.2 Genomic coordinates (GRCh38): 5:73,498,442-73,505,667 (from NCBI)

This gene has 14 transcripts (splice variants), 169 orthologues and 3 paralogues. Ubiquitous expression in ovary (RPKM 354.7), bone marrow (RPKM 186.5) and 25 other tissues.

Summary

This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]

BTF3 Products(4)

mRNA Protein Name
NM_001037637.2 NP_001032726.1 transcription factor BTF3 isoform A
NM_001207.5 NP_001198.2 transcription factor BTF3 isoform B
NM_001393652.1 NP_001380581.1 transcription factor BTF3 isoform C
NM_001393653.1 NP_001380582.1 transcription factor BTF3 isoform D

BTF3 Protein Structure

NAC

NAC: NAC domain (85 - 141)

  • 0
  • 100
  • 206 a.a.
Protein Preferred Names Protein Names

transcription factor BTF3

NAC-beta

Related Diseases

Diseases Alias
Ciliary Dyskinesia, Primary, 14

Primary Ciliary Dyskinesia 14

CILD14

Primary Ciliary Dyskinesia 14 With Or Without Situs Inversus

Ciliary Dyskinesia, Primary, 14, With Or Without Situs Inversus

Ics14

Immotile Cilia Syndrome 14

Dyskinesia, Ciliary, Primary, Type 14
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-164144 EPZ033294 / Unkown
HY-RS01660 BTF3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01661 BTF3L4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus BTF3 MGD MGI:1202875
Rattus norvegicus BTF3 RGD RGD:1308095
Canis familiaris BTF3 VGNC VGNC:52111
Bos taurus BTF3 VGNC VGNC:26595
Felis catus BTF3 VGNC VGNC:102168
Others BTF3 NCBI