2. Gene
  3. TARS1 - threonyl-tRNA synthetase 1 Gene

TARS1 - threonyl-tRNA synthetase 1 Gene

  • Gene
  • Protein
Homo sapiens (human)

Also known as TARS; TTD7; ThrRS

Gene ID: 6897 | Gene type: protein coding

About TARS1

Summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking Amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II Aminoacyl-tRNA Synthetase family [provided by RefSeq, Jul 2008]

TARS1 Products(1)

mRNA Protein Name
NR_047677.2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables ATP binding IMP
IMP: Inferred from mutant phenotype
25824639 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
25824639 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables threonine-tRNA ligase activity IDA
IDA: Inferred from direct assay
25824639 GOA
enables zinc ion binding IDA
IDA: Inferred from direct assay
25824639 GOA
Biological Process GO Annotation Evidence Reference Source
involved in threonyl-tRNA aminoacylation IDA
IDA: Inferred from direct assay
25824639 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

threonine--tRNA ligase 1, cytoplasmic

threonine tRNA ligase 1, cytoplasmic

threonine--tRNA ligase, cytoplasmic

threonyl-tRNA synthetase, cytoplasmic

TARS1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
TARS1 P26639 SULT1B1 Homo sapiens O43704
Validated Y2H
32814053
Intra
TARS1 P26639 SULT1B1 Homo sapiens O43704
Y2H Array
32814053
Intra
TARS1 P26639 SULT1B1 Homo sapiens O43704
Y2H Pooling
32814053
Intra
TARS1 P26639 TARS3 Homo sapiens A2RTX5
Y2H Prey Pooling
25416956
Intra
TARS1 P26639 TARS3 Homo sapiens A2RTX5
Y2H Prey Pooling
32296183
Intra
TARS1 P26639 TARS3 Homo sapiens A2RTX5
Y2H Array
25416956
Intra
TARS1 P26639 TARS3 Homo sapiens A2RTX5
Y2H Array
32296183
Intra
TARS1 P26639 C7orf25 Homo sapiens Q9BPX7
Y2H Array
25416956
Intra
TARS1 P26639 C7orf25 Homo sapiens Q9BPX7
Validated Y2H
25416956
Intra
TARS1 P26639 C7orf25 Homo sapiens Q9BPX7
Y2H Prey Pooling
25416956
Intra
TARS1 P26639 OPTN Homo sapiens Q96CV9
Validated Y2H
32814053
Intra
TARS1 P26639 OPTN Homo sapiens Q96CV9
Y2H Pooling
32814053
Intra
TARS1 P26639 OPTN Homo sapiens Q96CV9
Y2H Array
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction