2. Gene
  3. MET - MET proto-oncogene, receptor tyrosine kinase Gene

MET - MET proto-oncogene, receptor tyrosine kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca mulatta
Gene ID: 704562 | Gene type: protein coding

About MET

Primary_assembly 3: 142,897,819-143,014,670 forward strand.Mmul_10:CM014338.1

This gene has 4 transcripts (splice variants), 207 orthologues and 53 paralogues.

MET Products(1)

mRNA Protein Name
NM_001168629.2 NP_001162100.2 hepatocyte growth factor receptor precursor

MET Protein Structure

Sema_MET

Sema_MET: cd11278 (43 - 534)

PSI

PSI: smart00423 (537 - 579)

IPT_plexin_repeat1

IPT_plexin_repeat1: cd01180 (581 - 674)

IPT_plexin_repeat2

IPT_plexin_repeat2: cd01179 (675 - 758)

IPT_plexin_repeat3

IPT_plexin_repeat3: cd01181 (760 - 855)

IPT

IPT: smart00429 (856 - 952)

PTKc_Met_Ron

PTKc_Met_Ron: cd05058 (1100 - 1361)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1400 a.a.
Protein Preferred Names Protein Names

hepatocyte growth factor receptor

met proto-oncogene (hepatocyte growth factor receptor)

Recombinant MET Proteins

Cat. No. Product Name Accession Purity
HY-P72935 HGFR Protein, Cynomolgus/Rhesus Macaque (HEK293) NP_001162100.1 (E25-T932) ≥95%
HY-P72936 HGFR Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) NP_001162100.1 (E25-T932) ≥95%
HY-P72937 HGFR Protein, Cynomolgus/Rhesus Macaque (HEK293, His) NP_001162100.2 (E25-T932) ≥95%

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13016 Cabozantinib Inhibitor 99.96% Yes
Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-12035 AMG-208 Inhibitor 99.86% Phase 2
HY-16446 SAR125844 Inhibitor 98.17% Phase 2
HY-50683 JNJ-38877605 Inhibitor 99.95% Phase 1
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99455 Bafisontamab Inhibitor 96.00% Phase 3
Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-114357A DS-1205b free base Inhibitor 99.92% Unkown
HY-157387 c-Met-IN-22 Inhibitor / Unkown
HY-123237 KRC-108 Inhibitor / Unkown
HY-162803 c-Met-IN-24 Inhibitor / Unkown
HY-161372 PARP1/c-Met-IN-1 Inhibitor / Unkown
HY-120908 c-Met-IN-16 Inhibitor / Unkown
HY-149675 VEGFR-2/c-Met-IN-2 Inhibitor / Unkown
HY-168135 PROTAC c-Met degrader-1 Degrader / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MET NCBI NCBI:4233
Canis familiaris MET NCBI NCBI:403438
Macaca fascicularis MET NCBI NCBI:102123512
Mus musculus MET NCBI NCBI:17295
Susscrofa domestica MET NCBI
Rattus norvegicus MET NCBI NCBI:24553