2. Gene
  3. THRSP - thyroid hormone responsive Gene

THRSP - thyroid hormone responsive Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as S14; Lpgp; THRP; LPGP1; SPOT14

Gene ID: 7069 | Gene type: protein coding

About THRSP

Cytogenetic location: 11q14.1 Genomic coordinates (GRCh38): 11:78,063,861-78,068,351 (from NCBI)

This gene has 1 transcript (splice variant), 179 orthologues and 1 paralogue. Biased expression in fat (RPKM 186.6) and liver (RPKM 77.1).

Summary

The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be expressed in lipogenic breast cancers, which suggests a role in controlling tumor lipid metabolism. [provided by RefSeq, Jul 2008]

THRSP Products(1)

mRNA Protein Name
NM_003251.4 NP_003242.1 thyroid hormone-inducible hepatic protein
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

THRSP Protein Structure

Spot_14

Spot_14: Thyroid hormone-inducible hepatic protein Spot 14 (1 - 143)

  • 0
  • 100
  • 146 a.a.
Protein Preferred Names Protein Names

thyroid hormone-inducible hepatic protein

SPOT14 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14502 THRSP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris THRSP VGNC VGNC:47356
Macaca mulatta THRSP VGNC VGNC:78351
Mus musculus THRSP MGD MGI:109126
Bos taurus THRSP VGNC VGNC:35848
Felis catus THRSP VGNC VGNC:81929
Rattus norvegicus THRSP RGD RGD:3859